中华胃肠外科杂志
中華胃腸外科雜誌
중화위장외과잡지
Chinese Journal of Gastrointestinal Surgery
2015年
10期
1011-1015
,共5页
肖书傲%丰帆%孙力%徐光辉%连肖%郭曼%柰超%刘震%刘书尚%张磊%蔡磊%柳金强%张洪伟
肖書傲%豐帆%孫力%徐光輝%連肖%郭曼%柰超%劉震%劉書尚%張磊%蔡磊%柳金彊%張洪偉
초서오%봉범%손력%서광휘%련초%곽만%내초%류진%류서상%장뢰%채뢰%류금강%장홍위
胃肿瘤%ABO血型%临床病理特征%预后
胃腫瘤%ABO血型%臨床病理特徵%預後
위종류%ABO혈형%림상병리특정%예후
Stomach neoplasms%ABO blood group%Clinicopathologic characteristics%Prognosis
目的：探讨ABO血型与胃癌患者预后的关系。方法回顾性分析2008年6月至2013年10月间西京医院消化外科诊断为胃癌并接受根治性手术治疗的2838例患者的临床及随访资料。比较不同临床病理特征下ABO血型﹙A、B、O及AB型)的分布情况,并比较不同ABO血型患者的5年总体生存率。结果 ABO血型与胃癌患者的临床病理特征无显著关联﹙均P>0.05)。A、B、O和AB血型患者的5年总体生存率分别为57.3%、54.7%、57.4%和53.5%,差异亦无统计学意义﹙P=0.772)。但在Ⅲ期和有吸烟史的亚组中,AB血型患者5年总体生存率均明显高于非AB血型者﹙Ⅲ期：44.7%比25.2%,P=0.014；吸烟史：74.9%比53.4%,P=0.044)。结论 ABO血型与胃癌患者的临床病理特征及预后均无明显关联；但对于Ⅲ期患者以及有吸烟史的患者,AB血型可提示相对更好的预后。
目的：探討ABO血型與胃癌患者預後的關繫。方法迴顧性分析2008年6月至2013年10月間西京醫院消化外科診斷為胃癌併接受根治性手術治療的2838例患者的臨床及隨訪資料。比較不同臨床病理特徵下ABO血型﹙A、B、O及AB型)的分佈情況,併比較不同ABO血型患者的5年總體生存率。結果 ABO血型與胃癌患者的臨床病理特徵無顯著關聯﹙均P>0.05)。A、B、O和AB血型患者的5年總體生存率分彆為57.3%、54.7%、57.4%和53.5%,差異亦無統計學意義﹙P=0.772)。但在Ⅲ期和有吸煙史的亞組中,AB血型患者5年總體生存率均明顯高于非AB血型者﹙Ⅲ期：44.7%比25.2%,P=0.014；吸煙史：74.9%比53.4%,P=0.044)。結論 ABO血型與胃癌患者的臨床病理特徵及預後均無明顯關聯；但對于Ⅲ期患者以及有吸煙史的患者,AB血型可提示相對更好的預後。
목적：탐토ABO혈형여위암환자예후적관계。방법회고성분석2008년6월지2013년10월간서경의원소화외과진단위위암병접수근치성수술치료적2838례환자적림상급수방자료。비교불동림상병리특정하ABO혈형﹙A、B、O급AB형)적분포정황,병비교불동ABO혈형환자적5년총체생존솔。결과 ABO혈형여위암환자적림상병리특정무현저관련﹙균P>0.05)。A、B、O화AB혈형환자적5년총체생존솔분별위57.3%、54.7%、57.4%화53.5%,차이역무통계학의의﹙P=0.772)。단재Ⅲ기화유흡연사적아조중,AB혈형환자5년총체생존솔균명현고우비AB혈형자﹙Ⅲ기：44.7%비25.2%,P=0.014；흡연사：74.9%비53.4%,P=0.044)。결론 ABO혈형여위암환자적림상병리특정급예후균무명현관련；단대우Ⅲ기환자이급유흡연사적환자,AB혈형가제시상대경호적예후。
[Abstact] Objective To investigate the relationship of ABO blood group with the clinicopathological characteristics in patients with gastric cancer and to assess whether the ABO blood group was associated with prognosis. Method Clinicopathological and follow-up data of 2838 patients with gastric cancer who underwent radical gastrectomy in our department from June 2008 to October 2013 were analyzed retrospectively. The distribution of ABO blood group under different clinicopathological characteristics and the overall 5-year survival of ABO blood group were compared. Results There were no significant differences in clinicopathological characteristics among patients with different ABO blood groups ﹙all P>0.05). The 5-year overall survival﹙OS) rates were 57.3% for patients with blood type A, 54.7% for type B, 57.4% for type O, and 53.5% for type AB. Though there was no significance difference of survival among ABO blood groups ﹙P=0.722), while the subgroup analysis indicated that stage Ⅲ patients of blood group Non-AB had a poorer OS compared to those of blood group AB ﹙25.2% vs. 44.7%, P=0.014); smoking patients of blood group Non-AB had a poorer OS compared to those of blood group AB ﹙53.4% vs. 74.9%, P=0.044). Conclusion Neither clinicopathological characteristics nor overall survival are associated with the ABO blood group, however, stage Ⅲ and smoking patients of blood group Non-AB have a poorer OS compared to those of blood group AB.
