中国感染控制杂志
中國感染控製雜誌
중국감염공제잡지
Chinese Journal of Infection Control
2015年
10期
697-700
,共4页
谢朝云%闫飞%熊永发%熊芸%孙静%杨忠玲
謝朝雲%閆飛%熊永髮%熊蕓%孫靜%楊忠玲
사조운%염비%웅영발%웅예%손정%양충령
创面感染%抗菌性,微生物%病原菌%耐药性%医院感染
創麵感染%抗菌性,微生物%病原菌%耐藥性%醫院感染
창면감염%항균성,미생물%병원균%내약성%의원감염
wound infection%drug resistance,microbial%pathogen%drug resistance%healthcare-associated infection
目的:分析创面感染病原菌的分布及耐药性,为临床治疗创面感染合理用药及减少耐药菌产生提供科学依据。方法对某院2011年6月—2014年4月患者创面感染标本中检出的病原菌资料进行回顾性分析。结果创面标本中共检出965株病原菌,感染部位以四肢为主(50.47%);科室分布以骨外科为主(44.97%);感染诊断以创伤及切口感染较多,分别占47.98%、36.48%。检出的病原菌中革兰阳性菌占37.20%,革兰阴性菌占59.59%,真菌占3.21%。主要革兰阳性菌对万古霉素、替考拉宁和利奈唑胺高度敏感,主要革兰阴性菌对头孢哌酮/舒巴坦、哌拉西林/他唑巴坦、亚胺培南和美罗培南敏感度较高外,对大多数常用的抗菌药物均有较高的耐药率。结论创面感染患者主要来源于骨科,以创伤与手术切口感染为主,且常见革兰阳性及阴性菌的耐药率均较高。外科医生尤其是骨科医生应加强病原菌培养及药敏监测,合理选用抗菌药物,同时加强手术部位感染的防控,以降低感染率和减少耐药菌的发生。
目的:分析創麵感染病原菌的分佈及耐藥性,為臨床治療創麵感染閤理用藥及減少耐藥菌產生提供科學依據。方法對某院2011年6月—2014年4月患者創麵感染標本中檢齣的病原菌資料進行迴顧性分析。結果創麵標本中共檢齣965株病原菌,感染部位以四肢為主(50.47%);科室分佈以骨外科為主(44.97%);感染診斷以創傷及切口感染較多,分彆佔47.98%、36.48%。檢齣的病原菌中革蘭暘性菌佔37.20%,革蘭陰性菌佔59.59%,真菌佔3.21%。主要革蘭暘性菌對萬古黴素、替攷拉寧和利奈唑胺高度敏感,主要革蘭陰性菌對頭孢哌酮/舒巴坦、哌拉西林/他唑巴坦、亞胺培南和美囉培南敏感度較高外,對大多數常用的抗菌藥物均有較高的耐藥率。結論創麵感染患者主要來源于骨科,以創傷與手術切口感染為主,且常見革蘭暘性及陰性菌的耐藥率均較高。外科醫生尤其是骨科醫生應加彊病原菌培養及藥敏鑑測,閤理選用抗菌藥物,同時加彊手術部位感染的防控,以降低感染率和減少耐藥菌的髮生。
목적:분석창면감염병원균적분포급내약성,위림상치료창면감염합리용약급감소내약균산생제공과학의거。방법대모원2011년6월—2014년4월환자창면감염표본중검출적병원균자료진행회고성분석。결과창면표본중공검출965주병원균,감염부위이사지위주(50.47%);과실분포이골외과위주(44.97%);감염진단이창상급절구감염교다,분별점47.98%、36.48%。검출적병원균중혁란양성균점37.20%,혁란음성균점59.59%,진균점3.21%。주요혁란양성균대만고매소、체고랍저화리내서알고도민감,주요혁란음성균대두포고동/서파탄、고랍서림/타서파탄、아알배남화미라배남민감도교고외,대대다수상용적항균약물균유교고적내약솔。결론창면감염환자주요래원우골과,이창상여수술절구감염위주,차상견혁란양성급음성균적내약솔균교고。외과의생우기시골과의생응가강병원균배양급약민감측,합리선용항균약물,동시가강수술부위감염적방공,이강저감염솔화감소내약균적발생。
Objective To analyze the distribution and antimicrobial resistance of pathogenic strains in wound infec-tion,and provide scientific evidence for rational use of antimicrobial agents in treatment of wound infection as well as reducing the emergence of drug-resistant organisms.Methods Data about pathogenic strains isolated from wound specimens of patients with wound infection in a hospital between June 2011 and April 2014 were analyzed retrospectively.Results A total of 965 pathogenic strains were isolated from wound specimens,the main infection sites were limbs(50.47%);infected patients mainly distributed in department of orthopaedic surgery(44.97%);trauma and incisional wound infection were the major infection types(47.98%,36.48%,respectively).Among iso-lated pathogens,gram-positive bacteria,gram-negative bacteria,and fungi accounted for 37.20%,59.59%,and 3.21 % respectively.The main gram-positive bacteria were highly susceptible to vancomycin,teicoplanin,and linezolid,the main gram-negative bacteria were highly resistant to most commonly used antimicrobial agents except cefoperazone/sulbactam,piperacillin/ tazobactam,imipenem,and meropenem.Conclusion Patients with wound infection are mainly distributed in department of orthopedics,the main infection types are trauma and surgical site infection,antimicrobial resistant rates of the major gram-positive and gram-negative bacteria are both high.Sur-geons,especially orthopedics surgeons,should pay attention to the culture of pathogens and monitoring of antimi-crobial susceptibility,use antimicrobial agents rationally,and strengthen the prevention and control of surgical site infection,so as to reduce the infection incidence and occurrence of drug-resistant organisms.