药学实践杂志
藥學實踐雜誌
약학실천잡지
Journal of Pharmaceutical Practice
2015年
6期
508-512
,共5页
CYP2C19%基因多态性%质子泵抑制剂%伏立康唑%氯吡格雷
CYP2C19%基因多態性%質子泵抑製劑%伏立康唑%氯吡格雷
CYP2C19%기인다태성%질자빙억제제%복립강서%록필격뢰
CYP2C19%polymorphism%proton pump inhibitor%voriconazole%clopidogrel
药物代谢和相互作用的差异与CYP的单核苷酸基因多态性有关。综述CYP2C19基因多态性对质子泵抑制剂、抗真菌药伏立康唑、抗血小板药氯吡格雷的代谢和药物相互作用的影响，以期为个体化用药提供参考。
藥物代謝和相互作用的差異與CYP的單覈苷痠基因多態性有關。綜述CYP2C19基因多態性對質子泵抑製劑、抗真菌藥伏立康唑、抗血小闆藥氯吡格雷的代謝和藥物相互作用的影響，以期為箇體化用藥提供參攷。
약물대사화상호작용적차이여CYP적단핵감산기인다태성유관。종술CYP2C19기인다태성대질자빙억제제、항진균약복립강서、항혈소판약록필격뢰적대사화약물상호작용적영향，이기위개체화용약제공삼고。
Drug metabolism and drug-drug interactions were associated with the single nucleotide polymorphisms of CYP .The relationship between CYP2C19 polymorphisms and metabolism as well as interactions of proton pump inhibitors , voriconazole and clopidogrel were reviewed to provide evidence for personalized medication .
