中国医药科学
中國醫藥科學
중국의약과학
China Medicine and Pharmacy
2015年
17期
19-22
,共4页
早期糖尿病肾病%养阴活血泄浊方%中药%安全性
早期糖尿病腎病%養陰活血洩濁方%中藥%安全性
조기당뇨병신병%양음활혈설탁방%중약%안전성
Early diabetic nephropathy%Yangyin Huoxue Xiezhuo Fang%Traditional Chinese medicine%Safety
目的 观察采用养阴活血泄浊方治疗早期糖尿病肾病的临床疗效.方法 回顾性分析76例早期糖尿病肾病患者资料,根据治疗方法分为治疗组(45例)和对照组(31例),均给予控制饮食、血糖、适量运动等糖尿病基础治疗,对照组采用西医常规治疗,并根据病情使用降糖药,在此基础上,治疗组加用养阴活血泄浊中药方剂,治疗周期为12周.观察两组治疗前后的实验室检查指标及不良反应.结果 治疗12周后,两组治疗后的各主要指标(FCG、HbAlC、TG、LDL-C、mAlb、UAER、hs-CRP、Cys C)均较治疗前有明显改善,差异有统计学意义(P<0.05);且治疗组治疗后的各值较对照组治疗后改善更明显,差异有统计学意义(P<0.05).结论 养阴活血泄浊方治疗早期糖尿病肾病能有效改善各主要实验指标值,具有较好的临床疗效,值得临床运用推广.
目的 觀察採用養陰活血洩濁方治療早期糖尿病腎病的臨床療效.方法 迴顧性分析76例早期糖尿病腎病患者資料,根據治療方法分為治療組(45例)和對照組(31例),均給予控製飲食、血糖、適量運動等糖尿病基礎治療,對照組採用西醫常規治療,併根據病情使用降糖藥,在此基礎上,治療組加用養陰活血洩濁中藥方劑,治療週期為12週.觀察兩組治療前後的實驗室檢查指標及不良反應.結果 治療12週後,兩組治療後的各主要指標(FCG、HbAlC、TG、LDL-C、mAlb、UAER、hs-CRP、Cys C)均較治療前有明顯改善,差異有統計學意義(P<0.05);且治療組治療後的各值較對照組治療後改善更明顯,差異有統計學意義(P<0.05).結論 養陰活血洩濁方治療早期糖尿病腎病能有效改善各主要實驗指標值,具有較好的臨床療效,值得臨床運用推廣.
목적 관찰채용양음활혈설탁방치료조기당뇨병신병적림상료효.방법 회고성분석76례조기당뇨병신병환자자료,근거치료방법분위치료조(45례)화대조조(31례),균급여공제음식、혈당、괄량운동등당뇨병기출치료,대조조채용서의상규치료,병근거병정사용강당약,재차기출상,치료조가용양음활혈설탁중약방제,치료주기위12주.관찰량조치료전후적실험실검사지표급불량반응.결과 치료12주후,량조치료후적각주요지표(FCG、HbAlC、TG、LDL-C、mAlb、UAER、hs-CRP、Cys C)균교치료전유명현개선,차이유통계학의의(P<0.05);차치료조치료후적각치교대조조치료후개선경명현,차이유통계학의의(P<0.05).결론 양음활혈설탁방치료조기당뇨병신병능유효개선각주요실험지표치,구유교호적림상료효,치득림상운용추엄.
Objective To observe the clinical efficacy and safety of treatment with Yangyin Huoxue Xiezhuo Fang on early diabetic nephropathy.Methods 76 patients with early diabetic nephropathy were divided into treatment group(45 cases)and control group(31 cases)follow the treatment methods retrospectively,and basic treatments for diabetes like controlling diet and blood glucose,exercising moderately were conducted on all patients;the control group used the conventional western medicine treatment,and hypoglycemic agents was used according to the disease,on that basis,the treatment group was given Yangyin Huoxue Xiezhuo Fang,and the treatment lasted for 12 weeks.The laboratory parameters before and after treatment,and adverse events were compared.Results After 12 weeks of treatment,the experimental index value(FCG、HbAlC、TG、LDL-C、mAlb、UAER、hs-CRP、Cys C)in both control group and treatment group were obviously improved comparing with that before treatment(P<0.05).The value in treatment group presented a better improvement than that in the control group after treatment(P<0.05).Conclusion Yangyin Huoxue Xiezhuo Fang on early diabetic nephropathy can effectively control the experimental index value,and has a good clinical efficacy that it is worth widely used in the clinic.
