CAJ | 학술논문

目的：探讨痰培养阳性者超敏C反应蛋白（hs‐CRP）和白细胞（WBC）变化情况。方法按病原菌菌种将116例痰培养阳性者分为5组，以痰培养阴性患者作为对照组。对患者进行hs‐CRP、WBC等指标检测，比较各组间各指标水平和异常检出率。结果与阴性组比较，5个痰培养阳性组hs‐CRP水平均明显升高（P＜0．05），以白假丝酵母菌组水平最高；除流感嗜血杆菌组外，其余4个阳性组WBC、中性粒细胞水平均明显升高（ P＜0．05），以肺炎链球菌组升高最明显。5个阳性组均有很高的hs‐CRP升高检出率。肺炎链球菌组WBC升高检出率为64．7％，与流感嗜血杆菌组比较差异有统计学意义（P＜0．05）。结论痰培养阳性者由于细菌感染或定植，大多会出现炎性反应。
목적：탐토담배양양성자초민C반응단백（hs‐CRP）화백세포（WBC）변화정황。방법안병원균균충장116례담배양양성자분위5조，이담배양음성환자작위대조조。대환자진행hs‐CRP、WBC등지표검측，비교각조간각지표수평화이상검출솔。결과여음성조비교，5개담배양양성조hs‐CRP수평균명현승고（P＜0．05），이백가사효모균조수평최고；제류감기혈간균조외，기여4개양성조WBC、중성립세포수평균명현승고（ P＜0．05），이폐염련구균조승고최명현。5개양성조균유흔고적hs‐CRP승고검출솔。폐염련구균조WBC승고검출솔위64．7％，여류감기혈간균조비교차이유통계학의의（P＜0．05）。결론담배양양성자유우세균감염혹정식，대다회출현염성반응。
Objective To investigate the change of high‐sensitivity C‐reactive protein(hs‐CRP) and white blood cell(WBC) in patients with positive sputum culture results .Methods hs‐CRP and WBC were determined in 116 patients with positive sputum culture results ,which were divided into 5 groups according to strains ,and control group of patients with negative sputum culture re‐sults .Levels and abnormal rates of various parameters were compared between each group .Results hs‐CRP levels significantly in‐creased in the 5 sputum culture positive groups ,compared with control group(P<0 .05) ,and that of Candida albicans group was the most high .WBC and neutrophile granulocyte(NEU) levels of 4 positive groups were obviously raised(P<0 .05) besides Haemophi‐lus influenzae group ,and the elevation tendency was the most obvious in Streptococcus pneumoniae group .The 5 positive groups were all with high detectable rates of hs‐CRP elevation .The detectable rate of WBC elevation in Streptococcus pneumoniae group was 64 .7% ,higher than Haemophilus influenzae group(P<0 .05) .Conclusion The majority of patients with positive sputum cul‐ture results could be with inflammatory response because of bacterial infection or colonization .