CAJ | 학술논문

目的：探讨不同方法联合检测在孕妇 TORCH感染中的应用价值。方法采用酶联免疫吸附法对孕妇进行血清TORCH特异性IgM抗体进行检测，孕妇每两周接受1次超声检查，观察胎儿发育情况。结果656例孕妇中，TORCH感染率为19．36％。其中弓形虫、风疹病毒、巨细胞病毒、单纯疱疹病毒特异性Ig M 抗体阳性率分别为3．50％、2．13％、4．27％、4．72％。T O RC H特异性抗体阳性者超声检查检出的胎儿发育异常包括脐膨出37例、颈部淋巴水囊肿12例、停止发育4例、脑积水6例、死胎9例、单脐动脉肾盂积水16例、腹裂12例、发育迟缓24例，总异常率为18．29％。656例妊娠妇女中，正常分娩574例，其中T O RC H感染者56例，占9．76％；妊娠结局不良82例，其中T O RC H感染43例，占52．44％，与正常分娩者中T O RC H感染者所占比例比较差异有统计学意义（P＜0．05）。结论超声与血清学检测联合应用于孕妇TORCH感染诊断，方法可靠，能够有效地提高人口素质。
목적：탐토불동방법연합검측재잉부 TORCH감염중적응용개치。방법채용매련면역흡부법대잉부진행혈청TORCH특이성IgM항체진행검측，잉부매량주접수1차초성검사，관찰태인발육정황。결과656례잉부중，TORCH감염솔위19．36％。기중궁형충、풍진병독、거세포병독、단순포진병독특이성Ig M 항체양성솔분별위3．50％、2．13％、4．27％、4．72％。T O RC H특이성항체양성자초성검사검출적태인발육이상포괄제팽출37례、경부림파수낭종12례、정지발육4례、뇌적수6례、사태9례、단제동맥신우적수16례、복렬12례、발육지완24례，총이상솔위18．29％。656례임신부녀중，정상분면574례，기중T O RC H감염자56례，점9．76％；임신결국불량82례，기중T O RC H감염43례，점52．44％，여정상분면자중T O RC H감염자소점비례비교차이유통계학의의（P＜0．05）。결론초성여혈청학검측연합응용우잉부TORCH감염진단，방법가고，능구유효지제고인구소질。
Objective To study the use of ultrasound and serological diagnosis of TORCH infection in pregnant women .Methods Enzyme linked immunosorbent assay of serum IgM antibodies specific for TORCH were performed .Biweekly ultrasonic inspec‐tion were also performed to detect fetal development .Results Among 656 cases of pregnant women ,the TORCH infection rate was 19 .36% ,and the positive rates of IgM specific for toxoplasma ,Rubella virus ,cytomegalovirus ,herpes simplex virus were 3 .50% , 2 .13% ,4 .27% and 4 .72% .Among TORCH antibody positive pregnant women ,ultrasound abnormality included 37 cases of omphalocele ,12 cases of cervical lymph hydrocyst ,4 cases of growth‐stopping ,6 cases of hydrocephalus ,9 cases of fetal death ,16 cases of single umbilical artery hydronephrosis ,12 cases of gastroschisis ,24 cases of intrauterine fetal growth retardation ,and the total abnormal rate was 18 .29% .Among 656 cases of pregnant women ,there are 574 cases of normal deliveries ,including 56 cases of TORCH infection ,accounting for 9 .76% ,and 82 cases with adverse pregnancy outcome ,including 43 cases of TORCH infection , accounting for 52 .44% ,which was higher than that in pregnant women with normal deliveries(P<0 .05) .Conclusion Ultrasound and serological diagnosis of TORCH infection could be reliable and effectively improve the quality of the population .