世界睡眠医学杂志
世界睡眠醫學雜誌
세계수면의학잡지
World Journal of Sleep Medicine
2015年
3期
171-174
,共4页
朱爱华%杨燕玲%刘春君%戴煌%王预建%徐状%慈书平
硃愛華%楊燕玲%劉春君%戴煌%王預建%徐狀%慈書平
주애화%양연령%류춘군%대황%왕예건%서상%자서평
睡眠呼吸暂停低通气综合征%阻塞性%高血压病%流行病学%随访
睡眠呼吸暫停低通氣綜閤徵%阻塞性%高血壓病%流行病學%隨訪
수면호흡잠정저통기종합정%조새성%고혈압병%류행병학%수방
Sleep apnea hypopnea syndrome%Obstructive%Hypertension%Epidemiological survey%Follow-up
目的 随访阻塞性睡眠呼吸暂停低通气综合征 ( OSAHS) 与高血压的关系. 方法 对1 868例人群进行前瞻性随访, 通过家访式调查, 随访期间每年进行1次体检, 检查血压、 血脂、 血糖、 心电图及X线胸片等, 随访时间为24年. 结果 1 868例中男性956例、 女性912例, 随访起点年龄范围53~82岁, 平均年龄 ( 63 ±6 ) 岁. 其中确诊OSAHS者598 (32.0%) 例, 无OSAHS (对照组) 1 270 (68.0%) 例. 随访终点OSAHS组高血压506 (84.6%) 例、对照组398 (31.3%) 例, P<0.01. 结论 OSAHS患者发生高血压可能性较一般人群高, 考虑OSAHS与发生高血压存在相关性. 通过24年随访, 提示OSAHS可能是高血压病的独立危险因素. 引起高血的机制可能与OSAHS导致的低氧血症等有关.
目的 隨訪阻塞性睡眠呼吸暫停低通氣綜閤徵 ( OSAHS) 與高血壓的關繫. 方法 對1 868例人群進行前瞻性隨訪, 通過傢訪式調查, 隨訪期間每年進行1次體檢, 檢查血壓、 血脂、 血糖、 心電圖及X線胸片等, 隨訪時間為24年. 結果 1 868例中男性956例、 女性912例, 隨訪起點年齡範圍53~82歲, 平均年齡 ( 63 ±6 ) 歲. 其中確診OSAHS者598 (32.0%) 例, 無OSAHS (對照組) 1 270 (68.0%) 例. 隨訪終點OSAHS組高血壓506 (84.6%) 例、對照組398 (31.3%) 例, P<0.01. 結論 OSAHS患者髮生高血壓可能性較一般人群高, 攷慮OSAHS與髮生高血壓存在相關性. 通過24年隨訪, 提示OSAHS可能是高血壓病的獨立危險因素. 引起高血的機製可能與OSAHS導緻的低氧血癥等有關.
목적 수방조새성수면호흡잠정저통기종합정 ( OSAHS) 여고혈압적관계. 방법 대1 868례인군진행전첨성수방, 통과가방식조사, 수방기간매년진행1차체검, 검사혈압、 혈지、 혈당、 심전도급X선흉편등, 수방시간위24년. 결과 1 868례중남성956례、 녀성912례, 수방기점년령범위53~82세, 평균년령 ( 63 ±6 ) 세. 기중학진OSAHS자598 (32.0%) 례, 무OSAHS (대조조) 1 270 (68.0%) 례. 수방종점OSAHS조고혈압506 (84.6%) 례、대조조398 (31.3%) 례, P<0.01. 결론 OSAHS환자발생고혈압가능성교일반인군고, 고필OSAHS여발생고혈압존재상관성. 통과24년수방, 제시OSAHS가능시고혈압병적독립위험인소. 인기고혈적궤제가능여OSAHS도치적저양혈증등유관.
Objective To explore the correlation between obstructive sleep hypopnea apnea syndrome( OSAHS) and hypertension.Methods Prospective Home-visit questionaires for 1 868 people were used from November 1989 to November 2013,accompanied by annual medical examinations including blood pressure, blood-fat, serum glucose, electrocardiogram and chest x-ray.Computer tomography was carried out When hypertension manifested,that was termination of follow-up,the period of follow-up lasted 24 years.Results Among 1 868 elderly people,598(32.0%)OSAHS patients were made.1 270(68.0%)non-OSAHS group.patients who developed into hypertension were 506/598(84.6%)in OSAHS group,and 398/1 270(31.3%),P<0.01)in non-OSAHS group,respectively.943 died at last in the course of 24 years,431/598(72.1%)in OSAHS group and 512/1 270(40.3%,P<0.01)in non-OSAHS group,respectively.Conclusion According to longtime follow-up,the probability of OS-AHS patients suffers from hypertension is larger than the normal.We consider that there is a correlation between OSAHS and hy-pertension.At the end of our 24 years follow-up,OSAHS may be an independent dangerous factor of hypertension.
