吉林医学
吉林醫學
길림의학
Jilin Medical Journal
2015年
17期
3747-3749
,共3页
夏春军%赵靓%孙晓奕
夏春軍%趙靚%孫曉奕
하춘군%조정%손효혁
宫颈癌%调强放疗%放疗反应
宮頸癌%調彊放療%放療反應
궁경암%조강방료%방료반응
Cervical cancer%Intensity - modulated radiotherapy%Radiation - induced reaction
目的：观察具有不良预后因素的宫颈癌术后患者行盆腔适形调强放疗（ intensity - modulated radiotherapy，IMRT）的急性放疗反应和近期疗效。方法：63例Ⅰ~Ⅱa 期具有不良预后因素的宫颈癌术后患者，随机分成调强放疗组和常规放疗组，观察两组急性放疗反应和近期疗效。结果：调强放疗组急性不良放疗反应轻，无3级以上不良反应。两组在皮肤（χ2=46.96）及下消化道（χ2=25.49）急性放疗反应方面比较，差异有统计学意义（P ﹤0.05）。两组放疗近期疗效及1年生存率比较，差异无统计学意义（P ﹥0.05）。结论：IMRT 进行宫颈癌术后放疗，患者急性放疗反应较轻。
目的：觀察具有不良預後因素的宮頸癌術後患者行盆腔適形調彊放療（ intensity - modulated radiotherapy，IMRT）的急性放療反應和近期療效。方法：63例Ⅰ~Ⅱa 期具有不良預後因素的宮頸癌術後患者，隨機分成調彊放療組和常規放療組，觀察兩組急性放療反應和近期療效。結果：調彊放療組急性不良放療反應輕，無3級以上不良反應。兩組在皮膚（χ2=46.96）及下消化道（χ2=25.49）急性放療反應方麵比較，差異有統計學意義（P ﹤0.05）。兩組放療近期療效及1年生存率比較，差異無統計學意義（P ﹥0.05）。結論：IMRT 進行宮頸癌術後放療，患者急性放療反應較輕。
목적：관찰구유불량예후인소적궁경암술후환자행분강괄형조강방료（ intensity - modulated radiotherapy，IMRT）적급성방료반응화근기료효。방법：63례Ⅰ~Ⅱa 기구유불량예후인소적궁경암술후환자，수궤분성조강방료조화상규방료조，관찰량조급성방료반응화근기료효。결과：조강방료조급성불량방료반응경，무3급이상불량반응。량조재피부（χ2=46.96）급하소화도（χ2=25.49）급성방료반응방면비교，차이유통계학의의（P ﹤0.05）。량조방료근기료효급1년생존솔비교，차이무통계학의의（P ﹥0.05）。결론：IMRT 진행궁경암술후방료，환자급성방료반응교경。
Objective To evaluate the efficacy and toxicity of intensity - modulated radiotherapy(IMRT)for postoperative irradiation on cervical cancer. Method 63 cervical squamous cell carcinoma patients were divided into the IMRT group and conventional radiotherapy group. Acute radiation reactions and the short - term efficacy of two groups were observed. Results There were lighter response rates of ra-dioepidermitis and lower gastrointestinal reactions in the IMRT group. The other adverse in two groups such as skin(χ2 = 46. 96)and lower digestive tract(χ2 = 25. 49)the difference was statistically signifcant. 1 - year survival rate was no statistical difference(P ﹥ 0. 05). Con-clusion IMRT is regarded as a safe,convenient and slight side - effect for postoperative irradiation on cervical cancer.
