国际脑血管病杂志
國際腦血管病雜誌
국제뇌혈관병잡지
International Journal of Cerebrovascular Diseases
2015年
8期
602-606
,共5页
脑梗死%疾病恶化%运动障碍%磁共振成像%危险因素
腦梗死%疾病噁化%運動障礙%磁共振成像%危險因素
뇌경사%질병악화%운동장애%자공진성상%위험인소
Brain Infarction%Disease Progression%Movement Disorders%Magnetic Resonance Imaging%Risk Factors
目的：探讨大脑中动脉(middle cerebral artery, MCA)穿支动脉供血区梗死患者弥散加权成像上梗死分布模式与进展性运动功能缺损( progressive motor deficits, PMD)的相关性。方法对新发MCA穿支动脉供血区梗死患者进行回顾性分析,PMD定义为发病5 d内美国国立卫生研究院卒中量表(National Institutes of Health Stroke Scale, NIHSS)运动项目评分增加>2分且持续>24 h。比较PMD组和非PMD组人口统计学特征、危险因素、临床表现和梗死分布特点。结果共纳入64例患者,男性26例,女性38例,年龄(67．5±10．8)岁；PMD组28例,非PMD组36例。 PMD组梗死位于后部侧脑室旁的比例(67．8%对25．0%；χ2=11．5, P<0．05)和基线 NIHSS 评分[(6．9±1．8)分对(4．3±1．2)分；t=2．42,P<0．05)]均显著高于非PMD组。多变量logistic回归分析显示,梗死呈后部侧脑室旁分布与 PMD 呈显著独立相关(优势比6．3,95%可信区间2．20~18．0；P<0．001)。结论梗死呈后部侧脑室旁分布模式可作为预测MCA穿支动脉供血区梗死患者PMD的神经影像学标记物。
目的：探討大腦中動脈(middle cerebral artery, MCA)穿支動脈供血區梗死患者瀰散加權成像上梗死分佈模式與進展性運動功能缺損( progressive motor deficits, PMD)的相關性。方法對新髮MCA穿支動脈供血區梗死患者進行迴顧性分析,PMD定義為髮病5 d內美國國立衛生研究院卒中量錶(National Institutes of Health Stroke Scale, NIHSS)運動項目評分增加>2分且持續>24 h。比較PMD組和非PMD組人口統計學特徵、危險因素、臨床錶現和梗死分佈特點。結果共納入64例患者,男性26例,女性38例,年齡(67．5±10．8)歲；PMD組28例,非PMD組36例。 PMD組梗死位于後部側腦室徬的比例(67．8%對25．0%；χ2=11．5, P<0．05)和基線 NIHSS 評分[(6．9±1．8)分對(4．3±1．2)分；t=2．42,P<0．05)]均顯著高于非PMD組。多變量logistic迴歸分析顯示,梗死呈後部側腦室徬分佈與 PMD 呈顯著獨立相關(優勢比6．3,95%可信區間2．20~18．0；P<0．001)。結論梗死呈後部側腦室徬分佈模式可作為預測MCA穿支動脈供血區梗死患者PMD的神經影像學標記物。
목적：탐토대뇌중동맥(middle cerebral artery, MCA)천지동맥공혈구경사환자미산가권성상상경사분포모식여진전성운동공능결손( progressive motor deficits, PMD)적상관성。방법대신발MCA천지동맥공혈구경사환자진행회고성분석,PMD정의위발병5 d내미국국립위생연구원졸중량표(National Institutes of Health Stroke Scale, NIHSS)운동항목평분증가>2분차지속>24 h。비교PMD조화비PMD조인구통계학특정、위험인소、림상표현화경사분포특점。결과공납입64례환자,남성26례,녀성38례,년령(67．5±10．8)세；PMD조28례,비PMD조36례。 PMD조경사위우후부측뇌실방적비례(67．8%대25．0%；χ2=11．5, P<0．05)화기선 NIHSS 평분[(6．9±1．8)분대(4．3±1．2)분；t=2．42,P<0．05)]균현저고우비PMD조。다변량logistic회귀분석현시,경사정후부측뇌실방분포여 PMD 정현저독립상관(우세비6．3,95%가신구간2．20~18．0；P<0．001)。결론경사정후부측뇌실방분포모식가작위예측MCA천지동맥공혈구경사환자PMD적신경영상학표기물。
Objective To investigate the relationship between the pattern of infarct distribution on diffusion-weight imaging (DWI) and progressive movement deficits (PMD) in patients with infarct in the perforator territory of the middle cerebral artery (MCA). Methods The patients with new infarction in the perforator territory of MCA were analyzed retrospectively. PMD was defined as an increase of at least 2 points on the motor item of the National Institutes of Health Stroke Scale (NIHSS) score persisting for at least 24 hours within 5 days of stroke onset. The demographic characteristics, risk factors, clinical presentation, and distribution characteristics of the infarcts in the PMD and non-PMD groups were compared. Results A total of 64 patients were enrol ed in the study, including 38 females and 26 males, aged 67. 5 ± 10. 8 years. There were 28 patients in the PMD group and 36 in the non-PMD group. The proportion of the infarcts located in the posterior paraventricular region (67. 8% vs. 25. 0%; χ2 =11. 5, P<0. 05) of the PMD group and the mean baseline NIHSS score (6. 9 ± 1. 8 vs. 4. 3 ± 1. 2; t=2. 42, P<0. 05) were significantly higher than those of the non-PMD group. Multiple logistic regression analysis showed that the posterior paraventricular type infarcts had significantly independently correlation with PMD (odds ratio 6. 31, 95% confidence interval 2. 20-18. 0; P<0. 001). Conclusions The posterior paraventricular type infarcts on DWI can be used as a neuroimaging marker for predicting PMD in patients with infarction in the perforator artery territory of MCA.
