国际麻醉学与复苏杂志
國際痳醉學與複囌雜誌
국제마취학여복소잡지
International Journal of Anesthesiology and Resuscitation
2015年
10期
922-924
,共3页
运动神经损伤%神经病理性疼痛%致炎细胞因子%神经胶质细胞
運動神經損傷%神經病理性疼痛%緻炎細胞因子%神經膠質細胞
운동신경손상%신경병이성동통%치염세포인자%신경효질세포
Motor nerve injury%Neuropathic pain%Proinflammatory cytokine%Glial cell
背景 神经病理性疼痛(neuropathic pain,NP)严重影响患者的生活质量和工作能力.人们曾经认为感觉神经损伤引起NP,而最新研究表明,运动神经损伤在其中发挥更重要的作用. 目的 指出运动神经损伤在NP中的重要作用,以引起基础和临床研究者的关注. 内容 讨论NP相关的实验和临床证据. 趋向 回复运动功能或兴奋运动相关脑区可抑制NP.
揹景 神經病理性疼痛(neuropathic pain,NP)嚴重影響患者的生活質量和工作能力.人們曾經認為感覺神經損傷引起NP,而最新研究錶明,運動神經損傷在其中髮揮更重要的作用. 目的 指齣運動神經損傷在NP中的重要作用,以引起基礎和臨床研究者的關註. 內容 討論NP相關的實驗和臨床證據. 趨嚮 迴複運動功能或興奮運動相關腦區可抑製NP.
배경 신경병이성동통(neuropathic pain,NP)엄중영향환자적생활질량화공작능력.인문증경인위감각신경손상인기NP,이최신연구표명,운동신경손상재기중발휘경중요적작용. 목적 지출운동신경손상재NP중적중요작용,이인기기출화림상연구자적관주. 내용 토론NP상관적실험화림상증거. 추향 회복운동공능혹흥강운동상관뇌구가억제NP.
Background Neuropathic pain (NP) that damages patient's life and working ability is still a big challenge for pain clinician.It has been once believed that sensory nerve injury induces NP.However, recent works show that motor nerve injury may play more important role.Objective The role of motor nerve injury for generation of NP was emphasized to attract attention of basic and clinical pain researchers.Content In this article the related experimental and clinical evidences were reviewed and discussed.Trend Restoring motor function or stimulating motor-related brain areas may be attenuate NP.