亚太热带医药杂志（英文版）
亞太熱帶醫藥雜誌（英文版）
아태열대의약잡지（영문판）
Asian pacific Journal of Tropical Medicine
2012年
1期
62-66
,共5页
Solanum aethiopicum%Inflammation%Oedema reduction%Granuloma tissue%Rats
Objective:To evaluate the possible anti-inflammatory effect of garden egg [Solanum aethiopicum (S. aethiopicum)] using experimentally induced inflammatory models in rats. Methods:Oedema was induced on the rat hind paw by the injection of 0.1 mL undiluted fresh egg albumin (philogistic agent) into the subplantar surface of the rat paw. Tissue granuloma was induced in the rats by the implantation of two autoclaved cotton pellets (30 mg) under the flank of previously shaved back of anaesthetised rats. Garden egg extract doses were administered to the rats for seven consecutive days. On day 8, the animals were killed and the pellets surrounded by granuloma tissue were dissected out and dried. Results:Extracts of garden egg significantly (P<0.05) reduced the fresh egg albumin-induced rat paw oedema and also significantly (P<0.05) reduced the granuloma tissue formation in the treated groups when compared to the control. Conclusions:This study shows that the fruits of garden egg (S. aethiopicum) have anti-inflammatory activity in the models studied.
