CAJ | 학술논문

目的：使用食物过敏生活质量问卷-父母版（FAQLQ - PF）调查食物过敏婴儿治疗前后的生活质量。方法应用特应性皮炎评分量表（EASI）对湿疹患儿50例中最终完成调查的46例进行临床症状评估；对46例食物过敏患儿进行规范化干预治疗2个月后，采用 FAQLQ - PF 和体格发育进行治疗前后的生活质量调查和评价。结果1.50例入组患儿中完成终末调查为46例，年龄为（4.78±1.48）个月，有变应性家族史者29例（63.04％）；其中鸡蛋过敏34例（73.91％），牛奶20例（43.48％），鱼虾4例（8.70％），胡萝卜2例（4.35％）。2.治疗前患儿 ESAI、FAQLQ - PF 评分分别为13.20±12.86、2.12±1.33；治疗后下降，分别为2.02±4.40、1.33±1.08，差异均有统计学意义（t ＝28.070、4.014，P 均﹤0.05）。3.治疗前后 FAQLQ - PF 各模块得分比较显示情绪影响、对食物的焦虑方面分值降低，分别由2.10±1.47、2.63±1.83下降为1.30±1.09、1.68±1.37，差异均有统计学意义（t ＝5.204、8.818，P 均﹤0.05）。4. EASI 与 FAQLQ - PF 评分之间存在显著正相关（ρ＝0.205，P ﹤0.05）。结论食物过敏对患儿生活质量有显著影响，随着疾病严重程度升高，其生活质量逐渐下降；规范化治疗后患儿及家长生活质量提高。
목적：사용식물과민생활질량문권-부모판（FAQLQ - PF）조사식물과민영인치료전후적생활질량。방법응용특응성피염평분량표（EASI）대습진환인50례중최종완성조사적46례진행림상증상평고；대46례식물과민환인진행규범화간예치료2개월후，채용 FAQLQ - PF 화체격발육진행치료전후적생활질량조사화평개。결과1.50례입조환인중완성종말조사위46례，년령위（4.78±1.48）개월，유변응성가족사자29례（63.04％）；기중계단과민34례（73.91％），우내20례（43.48％），어하4례（8.70％），호라복2례（4.35％）。2.치료전환인 ESAI、FAQLQ - PF 평분분별위13.20±12.86、2.12±1.33；치료후하강，분별위2.02±4.40、1.33±1.08，차이균유통계학의의（t ＝28.070、4.014，P 균﹤0.05）。3.치료전후 FAQLQ - PF 각모괴득분비교현시정서영향、대식물적초필방면분치강저，분별유2.10±1.47、2.63±1.83하강위1.30±1.09、1.68±1.37，차이균유통계학의의（t ＝5.204、8.818，P 균﹤0.05）。4. EASI 여 FAQLQ - PF 평분지간존재현저정상관（ρ＝0.205，P ﹤0.05）。결론식물과민대환인생활질량유현저영향，수착질병엄중정도승고，기생활질량축점하강；규범화치료후환인급가장생활질량제고。
Objective To investigate the life quality in infants with food allergy before and after treatment by using of Food Allergy Quality of Life Questionnaire - Parent Form(FAQLQ - PF). Methods The severity of eczema in 46 children with food allergy was determined by eczema area and severity index(EASI). The life quality of such infants was assessed by the FAQLQ - PF after 2 - months treatment. Results (1)Among the 50 subjects,46(92% )respon-ded to the tests;the average age was(4. 78 ± 1. 48)months. Twenty - nine(63. 04% )subjects had family history of allergic disease. Egg(73. 91% )was the most common allergen,followed by cow milk(43. 48% ),fish and shrimp (8. 70% ),and carrot(4. 35% ).(2)The scores of EASI,FAQLQ - PF in children with food allergy before treatment were 13. 20 ± 12. 86 and 2. 12 ± 1. 33,respectively,the scores after treatment declined(2. 02 ± 4. 40 and 1. 33 ± 1. 08, respectively),there was a statistical significance(t = 28. 070,4. 014,all P ﹤ 0. 05).(3)Compared with pre - treat-ment,the scores of emotional impact subscale and food anxiety subscale declined,from 2. 10 ± 1. 47 and 2. 63 ± 1. 83 to 1. 30 ± 1. 09 and 1. 68 ± 1. 37,respectively,and there were statistically significant differences(t = 5. 204,8. 818,all P ﹤ 0. 05).(4)There was a positive correlation between the EASI and FAQLQ - PF scores(ρ = 0. 205,P ﹤ 0. 05). Conclusions Food allergy adversely affects the quality of life in infants. The poor life quality is associated with more severe symptoms. The life quality in infants and parents can be improved by standardized treatment.