中华实用儿科临床杂志
中華實用兒科臨床雜誌
중화실용인과림상잡지
Journal of Applied Clinical Pediatrics
2015年
21期
1607-1610
,共4页
儿童%缓解期%系统性红斑狼疮%评估%生活质量
兒童%緩解期%繫統性紅斑狼瘡%評估%生活質量
인동%완해기%계통성홍반랑창%평고%생활질량
Child%Remission%Systemic lupus erythematosus%Assessment%Quality of life
随着系统性红斑狼疮（systemic lupus erythematosus，SLE）发病机制研究的不断深入，治疗方案的不断改进，该病的预后已显著改善，长期生存率明显提高。在漫长的缓解期治疗中，儿科医师规范进行临床监测评估及指导合理用药对改善疾病预后、提高患儿生活质量非常重要。现参考欧洲抗风湿病联盟（EULAR）提出的对 SLE 患者进行监测的方法及中华医学会儿科学分会免疫学组制定的“儿童系统性红斑狼疮诊疗建议”，结合临床经验作如下推荐。
隨著繫統性紅斑狼瘡（systemic lupus erythematosus，SLE）髮病機製研究的不斷深入，治療方案的不斷改進，該病的預後已顯著改善，長期生存率明顯提高。在漫長的緩解期治療中，兒科醫師規範進行臨床鑑測評估及指導閤理用藥對改善疾病預後、提高患兒生活質量非常重要。現參攷歐洲抗風濕病聯盟（EULAR）提齣的對 SLE 患者進行鑑測的方法及中華醫學會兒科學分會免疫學組製定的“兒童繫統性紅斑狼瘡診療建議”，結閤臨床經驗作如下推薦。
수착계통성홍반랑창（systemic lupus erythematosus，SLE）발병궤제연구적불단심입，치료방안적불단개진，해병적예후이현저개선，장기생존솔명현제고。재만장적완해기치료중，인과의사규범진행림상감측평고급지도합리용약대개선질병예후、제고환인생활질량비상중요。현삼고구주항풍습병련맹（EULAR）제출적대 SLE 환자진행감측적방법급중화의학회인과학분회면역학조제정적“인동계통성홍반랑창진료건의”，결합림상경험작여하추천。
Systemic lupus erythematosus(SLE)is a multisystem autoimmune rheumatic disease characterized by flares and remissions. SLE has protean and often complex manifestations,necessitating careful clinical assessment. Not all clinical problems reported by a lupus child are due to the disease. Some may be a consequence of therapy and others may be unrelated to lupus. Therefore it is important to understand the totality of the effect of the disease on the patient. In order to do this measures are needed which distinguish current,potentially reversible disease activity,perma-nent organ damage and the effect of the disease on the children's health status. This paper discuss the current measures available to assess disease activity and damage in SLE.
