中华眼外伤职业眼病杂志
中華眼外傷職業眼病雜誌
중화안외상직업안병잡지
Chinese Journal of ocular trauma and occupational eye disease
2015年
6期
443-447
,共5页
青光眼,难治性%Ahmed青光眼阀%柔质材料FP8%硬质材料S3%效果比较
青光眼,難治性%Ahmed青光眼閥%柔質材料FP8%硬質材料S3%效果比較
청광안,난치성%Ahmed청광안벌%유질재료FP8%경질재료S3%효과비교
Glaucoma,refractory%Ahmed glaucoma valve implantation%Soft material FP8%Hard material S3%Comparison,effect
目的 比较柔质材料FP8与硬质材料S3 Ahmed青光眼阀植入术治疗难治性青光眼的临床效果.方法 柔质Ahmed青光眼阀植入术组(FP8组)30例(31眼)和硬质Ahmed青光眼阀植入术组(S3组)29例(31眼),测定术前、术后眼压,以光学生物测量仪测定术后功能性滤过泡形成率,术后7d进行前房穿刺,取房水进行炎症因子的检测.比较术后两组用药情况和并发症.结果 术后30、90、180 d的眼压FP8组均明显比S3组低(P＜0.05);FP8组功能性滤过泡形成率比S3组多(P ＜0.05);FP8组术后降眼压用药数量低于S3组(P＜0.05);术后7d时,FP8组血管细胞间粘附分子的表达量明显低于S3组(P＜0.05);而两组术后并发症差异无统计学意义(P＞0.05).结论 柔质材料FP8Ahmed青光眼阀植入术比硬质材料S3 Ahmed青光眼阀植入术在降低术后眼压、增加术后功能性滤过泡形成率、减轻术后炎症反应、减少术后用药量方面具有优势,是治疗难治性青光眼的优质材料.
目的 比較柔質材料FP8與硬質材料S3 Ahmed青光眼閥植入術治療難治性青光眼的臨床效果.方法 柔質Ahmed青光眼閥植入術組(FP8組)30例(31眼)和硬質Ahmed青光眼閥植入術組(S3組)29例(31眼),測定術前、術後眼壓,以光學生物測量儀測定術後功能性濾過泡形成率,術後7d進行前房穿刺,取房水進行炎癥因子的檢測.比較術後兩組用藥情況和併髮癥.結果 術後30、90、180 d的眼壓FP8組均明顯比S3組低(P＜0.05);FP8組功能性濾過泡形成率比S3組多(P ＜0.05);FP8組術後降眼壓用藥數量低于S3組(P＜0.05);術後7d時,FP8組血管細胞間粘附分子的錶達量明顯低于S3組(P＜0.05);而兩組術後併髮癥差異無統計學意義(P＞0.05).結論 柔質材料FP8Ahmed青光眼閥植入術比硬質材料S3 Ahmed青光眼閥植入術在降低術後眼壓、增加術後功能性濾過泡形成率、減輕術後炎癥反應、減少術後用藥量方麵具有優勢,是治療難治性青光眼的優質材料.
목적 비교유질재료FP8여경질재료S3 Ahmed청광안벌식입술치료난치성청광안적림상효과.방법 유질Ahmed청광안벌식입술조(FP8조)30례(31안)화경질Ahmed청광안벌식입술조(S3조)29례(31안),측정술전、술후안압,이광학생물측량의측정술후공능성려과포형성솔,술후7d진행전방천자,취방수진행염증인자적검측.비교술후량조용약정황화병발증.결과 술후30、90、180 d적안압FP8조균명현비S3조저(P＜0.05);FP8조공능성려과포형성솔비S3조다(P ＜0.05);FP8조술후강안압용약수량저우S3조(P＜0.05);술후7d시,FP8조혈관세포간점부분자적표체량명현저우S3조(P＜0.05);이량조술후병발증차이무통계학의의(P＞0.05).결론 유질재료FP8Ahmed청광안벌식입술비경질재료S3 Ahmed청광안벌식입술재강저술후안압、증가술후공능성려과포형성솔、감경술후염증반응、감소술후용약량방면구유우세,시치료난치성청광안적우질재료.
Objective To compare the effect of the soft material FP8 and the hard material S3 Ahmed glaucoma valve implantation for refractory glaucoma.Methods Thirty-one eyes of 30 cases of soft Ahmed glaucoma valve implantation (FP8 group) and thirty-one eyes of 29 cases of hard Ahmed glaucoma valve implantation (S3 group) were collected in this study.The postoperative and preoperative intraocular pressure was measured.The postoperative functional filtering bleb formation rate was determined by optical biological measurement instrument.The inflammatory factors in aqueous humor through paracentesis were detected on the seventh day after the operation.The medicine utilization and complications in patients of the two groups after the operation were observed.Results The intraocular pressure on the 30 days, 90 days and 180 days after the surgery were decreased in FP8 Ahmed group when compared with that in S3 group (P ＜ 0.05).The functional filtering bleb formation rate after the surgery were higher in FP8 Ahmed group than that in S3 group (P ＜ 0.05).The number of the ocular hypotensive agents after the surgery was less in FP8 Ahmed group than that in S3 group (P ＜ 0.05).The expression of VCAM-1 was less in FP8 group when compared with that in S3 group on the seventh day after the operation (P ＜ 0.05).There were no statistically significant difference in the postoperative complications between the two groups (P ＞ 0.05).Conclusion Ahmed glaucoma valve implantation with FP8 has more advantages in reducing postoperative intraocular pressure, increasing the rate of postoperative functional filtering bleb formation, reducing postoperative inflammatory reaction and anti-glaucoma medicine.It is a good choice for refractory glaucoma.
