药品评价
藥品評價
약품평개
Drug Evaluation
2015年
14期
36-39
,共4页
氯吡格雷%门诊处方%剂量%应用分析
氯吡格雷%門診處方%劑量%應用分析
록필격뢰%문진처방%제량%응용분석
clopidogrel%outpatient prescription%dose%application analysis
目的:通过对天津地区三级医院门诊用药调查,分析氯吡格雷的临床应用现状,为临床合理用药提供参考.方法:通过《医院处方分析合作项目》收集天津地区三级医院2011~2014年门诊处方,提取含氯吡格雷的处方,根据相关信息进行统计分析.结果:在所有调查的门诊处方中,含氯吡格雷的处方共67397张,处方中男性患者多于女性,年龄主要集中在50~79岁,且多数患有高血压、冠状动脉粥样硬化性心脏病、偏瘫、高脂血症、脑梗塞等疾病.用法为每次75mg/d(79.09%)、50mg/d(19.52%)或25mg/d(0.99%).其他用法用量出现较少.结论:使用氯吡格雷的患者多为患高血压和冠心病的老年男性,部分临床医师在使用氯吡格雷时,医嘱用法用量未遵循说明书和相关临床应用指南,应用25mg/d的维持剂量存在不合理性.部分门诊处方出现无诊断用药.建议加强医师对用药知识的了解和临床药师用药指导和监督,规范门诊处方,以提高临床合理用药水平.
目的:通過對天津地區三級醫院門診用藥調查,分析氯吡格雷的臨床應用現狀,為臨床閤理用藥提供參攷.方法:通過《醫院處方分析閤作項目》收集天津地區三級醫院2011~2014年門診處方,提取含氯吡格雷的處方,根據相關信息進行統計分析.結果:在所有調查的門診處方中,含氯吡格雷的處方共67397張,處方中男性患者多于女性,年齡主要集中在50~79歲,且多數患有高血壓、冠狀動脈粥樣硬化性心髒病、偏癱、高脂血癥、腦梗塞等疾病.用法為每次75mg/d(79.09%)、50mg/d(19.52%)或25mg/d(0.99%).其他用法用量齣現較少.結論:使用氯吡格雷的患者多為患高血壓和冠心病的老年男性,部分臨床醫師在使用氯吡格雷時,醫囑用法用量未遵循說明書和相關臨床應用指南,應用25mg/d的維持劑量存在不閤理性.部分門診處方齣現無診斷用藥.建議加彊醫師對用藥知識的瞭解和臨床藥師用藥指導和鑑督,規範門診處方,以提高臨床閤理用藥水平.
목적:통과대천진지구삼급의원문진용약조사,분석록필격뢰적림상응용현상,위림상합리용약제공삼고.방법:통과《의원처방분석합작항목》수집천진지구삼급의원2011~2014년문진처방,제취함록필격뢰적처방,근거상관신식진행통계분석.결과:재소유조사적문진처방중,함록필격뢰적처방공67397장,처방중남성환자다우녀성,년령주요집중재50~79세,차다수환유고혈압、관상동맥죽양경화성심장병、편탄、고지혈증、뇌경새등질병.용법위매차75mg/d(79.09%)、50mg/d(19.52%)혹25mg/d(0.99%).기타용법용량출현교소.결론:사용록필격뢰적환자다위환고혈압화관심병적노년남성,부분림상의사재사용록필격뢰시,의촉용법용량미준순설명서화상관림상응용지남,응용25mg/d적유지제량존재불합이성.부분문진처방출현무진단용약.건의가강의사대용약지식적료해화림상약사용약지도화감독,규범문진처방,이제고림상합리용약수평.
Objective: Through the outpatient drug investigation of the tertiary hospitals of tianjin region, the status quo of clinical application of clopidogre was analyzed, to provide reference for clinical rational drug use.Method:According to the relevant pharmacy data, originating from"Hospital prescription analysis of cooperation projects"in Tianjin outpatient prescriptions in 2011~2014, prescription containing clopidogrel was extracted, according to the relevant information for statistical analysis.Result: All the survey of outpatient prescriptions, including the prescriptions of clopidogrel were 67397, and prescriptions of men more than women, mainly concentrated in 50~79 years old, and most people with high blood pressure, coronary atherosclerosis, heart disease, hemiplegia, hyperlipidemia, cerebral infarction and other diseases. Usage for each is 75mg/d(79.09%), 50mg/d(19.52%) or 25mg/d(0.99%). Other dosage appears less.Conclusion: Most of the use of clopidogrel in patients with hypertension and coronary heart disease are for older men. Part of clinicians does not follow the instructions dosage and clinical application guides. Application of 25mg/d maintenance dose for the existence is not irrational. Part outpatient prescription drugs appear no diagnosis guidance. It proposed to strengthen the understanding of medication knowledge of physicians and clinical pharmacists' medication guide and supervise, regulate outpatient prescriptions to improve the level of rational drug use.
