CAJ | 학술논문

试验选用副猪嗜血杆菌血清型5型 LY02分离株通过腹腔注射感染仔猪，成功复制出副猪嗜血杆菌病的典型临床症状及病理变化。感染猪主要临床症状表现为发热、被毛粗乱、厌食、呼吸困难、腹式呼吸、关节肿大、跛行；剖检变化主要表现为胸腹腔严重的纤维素性渗出、关节积液等；组织病理学主要以肺脏间质性肺炎，肝脏局灶性坏死，心脏心肌纤维萎缩，脾脏红髓扩张、白髓萎缩、淋巴细胞衰减等变化为主。结果表明，本分离株为高致病力潜力菌株。
시험선용부저기혈간균혈청형5형 LY02분리주통과복강주사감염자저，성공복제출부저기혈간균병적전형림상증상급병리변화。감염저주요림상증상표현위발열、피모조란、염식、호흡곤난、복식호흡、관절종대、파행；부검변화주요표현위흉복강엄중적섬유소성삼출、관절적액등；조직병이학주요이폐장간질성폐염，간장국조성배사，심장심기섬유위축，비장홍수확장、백수위축、림파세포쇠감등변화위주。결과표명，본분리주위고치병력잠력균주。
The 15-day-old piglets were intraperitoneally inoculated with the LY02 strain of Haemophilus parasuis serotype 5 and typical signs and lesions of Glasser's disease were successfully reproduced. Piglets challenged showed significantly elevated temperatures, anorexia, dyspnoea, swollen joints, lameness and severe gross and pathological lesions, characterized by arthritis, fibrinosuppurative polyserositis in the pericardial, pleural and peritoneal cavities. The histopathological changes include interstitial pneumonia, focal necrosis of liver, cardiac dilatation, and red pulp dilatation, white pulp atrophy and lymphocyte depletion of spleen. The results indicated the LY02 strain would be a highly pathogenic strain.