CAJ | 학술논문

目的：探讨纳美芬联合盐酸羟考酮对上腹部手术患者麻醉苏醒期躁动的影响。方法：上腹部手术患者随机分为盐酸羟考酮组（A组），纳美芬联合盐酸羟考酮组（B组），术后用P C A镇痛，记录麻醉诱导前、术后1、6、12、24、48h的H R、S P O2、SBP/DBP、躁动发生率、Ramsay评分及疼痛视觉模拟评分(VAS)情况。结果：B组患者Ramsay评分较A组高(P<0.05)、躁动发生率、恶心呕吐发生率、和V A S评分和较A组低(P<0.05)。结论：纳美芬联合盐酸羟考酮用于上腹部手术后镇痛可减少麻醉苏醒期躁动发生率，减少胃肠道不良反应发生。
목적：탐토납미분연합염산간고동대상복부수술환자마취소성기조동적영향。방법：상복부수술환자수궤분위염산간고동조（A조），납미분연합염산간고동조（B조），술후용P C A진통，기록마취유도전、술후1、6、12、24、48h적H R、S P O2、SBP/DBP、조동발생솔、Ramsay평분급동통시각모의평분(VAS)정황。결과：B조환자Ramsay평분교A조고(P<0.05)、조동발생솔、악심구토발생솔、화V A S평분화교A조저(P<0.05)。결론：납미분연합염산간고동용우상복부수술후진통가감소마취소성기조동발생솔，감소위장도불량반응발생。
ObjectiveTo investigate the effects of oxycodone hydrochloride and nalmefene on emergence agitation and Hemodynamics of patients undergoing upper abdominal operation.MethodsASA gradeⅠ-Ⅱ patients undergoing elective upper abdominal operation were randomly divided into two groups: oxycodone hydrochloride group (group A), nalmefene and oxycodone hydrochloride group (group B) with 30 patients in each group, after the operation, the incidence of agitation, SBP/DBP, HR, SPO2,VAS score and Ramsay sedation score were recorded at the following time points: before induction of anesthesia, 1, 6, 12, 24, 48 hours after operation.ResultsCompared with group B, Ramsay sedation scores of patients in group A were slightly lower (P<0.05); the incidence and degree of agitation in B group were lower than A group (P<0.01).ConclusionOxycodone hydrochloride combined with nalmefene can make patients quiet cooperation and reduce emergence agitation during recovery period after upper abdominal operation.