CAJ | 학술논문

过敏性结膜炎是机体在遇到外界抗原时,免疫系统表现出的一种眼部异常超敏反应,其症状涉及整个眼表,包括眼睑、结膜、角膜、泪膜,患者表现为眼睑水肿、痒、结膜充血、流泪、畏光等,严重影响患者的健康和生活.过敏性结膜炎的发病机制尚不完全清楚,涉及IgE介导的Ⅰ型超敏反应,也有T淋巴细胞介导的细胞免疫反应.本文讨论T细胞及其细胞因子在过敏性结膜炎发病机制中作用的研究现状.
과민성결막염시궤체재우도외계항원시,면역계통표현출적일충안부이상초민반응,기증상섭급정개안표,포괄안검、결막、각막、루막,환자표현위안검수종、양、결막충혈、류루、외광등,엄중영향환자적건강화생활.과민성결막염적발병궤제상불완전청초,섭급IgE개도적Ⅰ형초민반응,야유T림파세포개도적세포면역반응.본문토론T세포급기세포인자재과민성결막염발병궤제중작용적연구현상.
Allergic conjunctivitis is an abnormal hypersensitivity response of the immune system to commonly encountered antigens.It is considered a syndrome that comprises the entire ocular surface,including lids, conjunctiva, cornea and tear film.The symptoms include eyelid edema, itching, conjunctival redness, tearing and light sensitivity.These symptoms and signs affect patients healthy and life seriously.The pathophysiology of allergic conjunctivitis is not completely clear.As far as we know, allergic eye disease might be caused by an immunoglobulin E (IgE)-mediated type Ⅰ hypersensitivity reaction, or a T-lymphocyte-mediated cellular immune response.This article mainly discuss the research status of T lymphocytes and its cytokines of allergic conjunctivitis and make a summary of its pathogenic mechanism.