CAJ | 학술논문

肿瘤是一种系统生物学疾病，治疗这一顽固疾病仅靠单一靶向药物已不太现实。本文将用系统生物学的观点，对肿瘤坏死因子相关凋亡配体（ TRAIL）与现今研究较热点的靶向药物以网络“network”联合方式，协同抗肿瘤进行一个综述。以期待为基于TRAIL个体化治疗肿瘤提供夯实的理论依据。
종류시일충계통생물학질병，치료저일완고질병부고단일파향약물이불태현실。본문장용계통생물학적관점，대종류배사인자상관조망배체（ TRAIL）여현금연구교열점적파향약물이망락“network”연합방식，협동항종류진행일개종술。이기대위기우TRAIL개체화치료종류제공항실적이론의거。
Tumor is a system-biology illness.Treatment of this intractable disease by any single medicine has not been realistic.In this review, we analyze the anti-tumor network of Tumor Necrosis Factor-related Apoptosis-indu-cing Ligand ( TRAIL ) by a system-biology technology and try to providecin individualized treatment strategy for TRAIL based therapy .