CAJ | 학술논문

目的探讨职业应激相关因素与血清中三碘甲状腺原氨酸(T3)、甲状腺素(T4)和促甲状腺激素(TSH)浓度的关系.方法以方便抽样与整群抽样方法抽取某市公安局某派出所的225名在职民警为研究对象.使用问卷调查其人口统计学特征和职业应激相关因素.采用放射免疫法对血清中T3、T4和TSH的浓度进行检测.应用SPSS13.0软件对数据进行t检验或方差分析、偏相关分析和多因素非条件logistic回归等统计学分析.结果回报与血清中T3浓度呈正相关(P＜0.05),每日紧张感与血清中T4浓度呈正相关(P＜0.05),心理需求、付出和每日紧张感与血清中TSH浓度呈负相关(均P＜0.05),睡眠质量与血清中TSH浓度呈正相关(P＜0.05);logistic回归分析显示,每日紧张感高评分组的血清中T3浓度升高的风险是低评分组的3.19倍,负性情绪高评分组的血清中T3浓度升高的风险是低评分组的1.32倍;负性情绪高评分组的血清中TSH浓度升高的风险是低评分组的0.43倍.结论职业应激相关因素与血清中甲状腺激素水平之间存在相关性;职业应激可导致血清中T3浓度升高,TSH浓度降低,但未发现对血清中T4浓度有影响.
목적 탐토직업응격상관인소여혈청중삼전갑상선원안산(T3)、갑상선소(T4)화촉갑상선격소(TSH)농도적관계.방법 이방편추양여정군추양방법추취모시공안국모파출소적225명재직민경위연구대상.사용문권조사기인구통계학특정화직업응격상관인소.채용방사면역법대혈청중T3、T4화TSH적농도진행검측.응용SPSS13.0연건대수거진행t검험혹방차분석、편상관분석화다인소비조건logistic회귀등통계학분석.결과 회보여혈청중T3농도정정상관(P＜0.05),매일긴장감여혈청중T4농도정정상관(P＜0.05),심리수구、부출화매일긴장감여혈청중TSH농도정부상관(균P＜0.05),수면질량여혈청중TSH농도정정상관(P＜0.05);logistic회귀분석현시,매일긴장감고평분조적혈청중T3농도승고적풍험시저평분조적3.19배,부성정서고평분조적혈청중T3농도승고적풍험시저평분조적1.32배;부성정서고평분조적혈청중TSH농도승고적풍험시저평분조적0.43배.결론 직업응격상관인소여혈청중갑상선격소수평지간존재상관성;직업응격가도치혈청중T3농도승고,TSH농도강저,단미발현대혈청중T4농도유영향.
Objective To explore the relationship of occupational stressors with the serum levels of triiodothyronine (T3),thyroxine (T4),and thyroid stimulating hormone (TSH).Methods Using convenience sampling and cluster sampling methods,225 policemen from a local police station in China were enrolled as subjects.Questionnaires were used to investigate demographic features and occupational stressors in those subjects.The serum levels of T3,T4,and TSH were measured by radioimmunoassay.The SPSS 13.0 software was used to perform t test or analysis of variance,partial correlation analysis,and multivariate non-conditional logistic regression analysis.Results Reward was positively correlated with the level of T3(P＜0.05).Daily tension was positively correlated with the level of T4 (P＜0.05).Psychological demand,effort,and daily tension were negatively correlated with the level of TSH (all P＜0.05).The quality of sleep was positively correlated with the level of TSH (P＜0.05).The logistic regression analysis revealed that the risk of increase in T3 level in the group with a high score for daily tension was 3.19-fold higher than that in the group with a low score,while the risk of increase in T3 level in the group with a high score for negative emotion was 1.32-fold higher than that in the group with a low score.The risk of increase in TSH level in the group with a high score for negative emotion was 0.43-fold that in the group with a low score.Conclusion The occupational stressors are correlated with the serum levels of thyroid hormones.Occupational stress can result in an increase in T3 level and a decrease in TSH level.However,occupational stress has no effect on T4 level.