中华消化杂志
中華消化雜誌
중화소화잡지
Chinese Journal of Digestion
2015年
10期
654-658
,共5页
沈玲燕%杜娟%张冰凌%陈春晓
瀋玲燕%杜娟%張冰凌%陳春曉
침령연%두연%장빙릉%진춘효
Crohn病%胶囊内镜克罗恩病活动指数评分%胶囊内镜评分指数%简化克罗恩病活动指数%C反应蛋白
Crohn病%膠囊內鏡剋囉恩病活動指數評分%膠囊內鏡評分指數%簡化剋囉恩病活動指數%C反應蛋白
Crohn병%효낭내경극라은병활동지수평분%효낭내경평분지수%간화극라은병활동지수%C반응단백
Crohn disease%CECDAI%Lewis score%SCDAI%C-reactive protein
目的 探讨胶囊内镜克罗恩病活动指数(CECDAI)评分、胶囊内镜评分指数(Lewis评分)、简化CD活动指数(简化CDAI)评分、血清CRP及 ESR评估CD的病变活动程度的相关性.方法 收集2009年4月至2014年4月行胶囊内镜检查并最终确诊为CD的患者120例 ,记录其血清CRP和ESR值.分别用CECDAI评分、Lewis评分、简化CDAI评分对患者CD病情活动程度进行评分.应用Spearman检验分析评估CECDAI评分、Lewis评分、简化CDAI评分、血清CRP水平及ESR水平间的相关性.结果 在全部患者中 ,CECDAI评分与Lewis评分有良好的相关性(r=0 .645 ,P<0 .01) ,与简化CDAI评分亦相关(r=0 .190 ,P<0 .05) ,与CRP、ESR有良好的相关性(r=0 .315、0 .393 ,P均<0 .01);但Lewis评分与简化 CDAI评分、CRP及 ESR无明显相关( r= 0 .052、0 .041、0 .021 ,P均>0 .05);CRP、ESR与简化CDAI评分有较好的相关性(r=0 .438、0 .429 ,P均<0 .01).在胶囊内镜未通过小肠的患者中 ,CECDAI评分与简化CDAI评分、CRP及 ESR均无明显相关性(r= 0 .126、0 .181、0 .269 ,P均>0 .05).结论 Lewis评分、简化CDAI评分、CRP和ESR均在能一定程度上反映CD患者的病情活动程度 ,CECDAI评分是评估CD患者病情活动程度的最适合指标 ,需重视胶囊内镜的检查.
目的 探討膠囊內鏡剋囉恩病活動指數(CECDAI)評分、膠囊內鏡評分指數(Lewis評分)、簡化CD活動指數(簡化CDAI)評分、血清CRP及 ESR評估CD的病變活動程度的相關性.方法 收集2009年4月至2014年4月行膠囊內鏡檢查併最終確診為CD的患者120例 ,記錄其血清CRP和ESR值.分彆用CECDAI評分、Lewis評分、簡化CDAI評分對患者CD病情活動程度進行評分.應用Spearman檢驗分析評估CECDAI評分、Lewis評分、簡化CDAI評分、血清CRP水平及ESR水平間的相關性.結果 在全部患者中 ,CECDAI評分與Lewis評分有良好的相關性(r=0 .645 ,P<0 .01) ,與簡化CDAI評分亦相關(r=0 .190 ,P<0 .05) ,與CRP、ESR有良好的相關性(r=0 .315、0 .393 ,P均<0 .01);但Lewis評分與簡化 CDAI評分、CRP及 ESR無明顯相關( r= 0 .052、0 .041、0 .021 ,P均>0 .05);CRP、ESR與簡化CDAI評分有較好的相關性(r=0 .438、0 .429 ,P均<0 .01).在膠囊內鏡未通過小腸的患者中 ,CECDAI評分與簡化CDAI評分、CRP及 ESR均無明顯相關性(r= 0 .126、0 .181、0 .269 ,P均>0 .05).結論 Lewis評分、簡化CDAI評分、CRP和ESR均在能一定程度上反映CD患者的病情活動程度 ,CECDAI評分是評估CD患者病情活動程度的最適閤指標 ,需重視膠囊內鏡的檢查.
목적 탐토효낭내경극라은병활동지수(CECDAI)평분、효낭내경평분지수(Lewis평분)、간화CD활동지수(간화CDAI)평분、혈청CRP급 ESR평고CD적병변활동정도적상관성.방법 수집2009년4월지2014년4월행효낭내경검사병최종학진위CD적환자120례 ,기록기혈청CRP화ESR치.분별용CECDAI평분、Lewis평분、간화CDAI평분대환자CD병정활동정도진행평분.응용Spearman검험분석평고CECDAI평분、Lewis평분、간화CDAI평분、혈청CRP수평급ESR수평간적상관성.결과 재전부환자중 ,CECDAI평분여Lewis평분유량호적상관성(r=0 .645 ,P<0 .01) ,여간화CDAI평분역상관(r=0 .190 ,P<0 .05) ,여CRP、ESR유량호적상관성(r=0 .315、0 .393 ,P균<0 .01);단Lewis평분여간화 CDAI평분、CRP급 ESR무명현상관( r= 0 .052、0 .041、0 .021 ,P균>0 .05);CRP、ESR여간화CDAI평분유교호적상관성(r=0 .438、0 .429 ,P균<0 .01).재효낭내경미통과소장적환자중 ,CECDAI평분여간화CDAI평분、CRP급 ESR균무명현상관성(r= 0 .126、0 .181、0 .269 ,P균>0 .05).결론 Lewis평분、간화CDAI평분、CRP화ESR균재능일정정도상반영CD환자적병정활동정도 ,CECDAI평분시평고CD환자병정활동정도적최괄합지표 ,수중시효낭내경적검사.
Objective To investigate the correlation between capsule endoscopy Crohn′s disease activity index (CECDAI ) , capsule endoscopy Lewis score , simplified Crohn′s disease activity index (sCDAI) ,C reactive protein (CRP) ,erythrocyte sedimentation rate (ESR) and Crohn′s disease (CD) activity .Methods From April 2009 to April 2014 , 120 patients having received capsule endoscopy examination and diagnosed as CD were collected . The data of CRP and ESR were analyzed . The CD severity was scored by CECDAI ,Lewis score and sCDAI .Spearman correlation was performed to analyze the correlation between CECDAI ,Lewis score ,sCDAI ,CRP and ESR .Results Among all the patients , CECDAI had a good correlation with Lewis score (r=0 .645 , P< 0 .01) and also was correlated with sCDAI (r=0 .190 , P< 0 .05) ,CRP and ESR (r= 0 .315 and 0 .393 ,both P< 0 .01) .However ,the Lewis score was not correlated with sCDAI ,CRP and ESR (r=0 .052 ,0 .041 and 0 .021 ,all P>0 .05) . sCDAI had a good correlation with CRP and ESR (r=0 .438 and 0 .429 ,both P<0 .01) .Among patients whose capsule endoscope failed to pass through the whole small intestinal ,the CECDAI had no significant correlation with sCDAI ,CRP and ESR (r=0 .126 ,0 .181 and 0 .269 ,all P>0 .05) .Conclusions Lewis score ,sCDAI ,CRP and ESR can reflect disease activity of CD patients in a certain degree .CECDAI is the most suitable index in evaluating the disease activity of CD patients .Therefore ,it is necessary to attach importance to capsule endoscopy examination .
