CAJ | 학술논문

腋窝淋巴结转移状态是乳腺癌患者最重要的预后决定因素之一.联合临床查体及超声、钼钯、CT、MRI、PET-CT等影像学检查可以提高预测准确率,但仍存在较高的假阴性率.超声引导下细针穿刺腋窝淋巴结能有效提高术前诊断率.结合患者的临床病理特征,利用数学及统计学方法构建预测前哨或非前哨淋巴结转移状态的模型可以计算其转移风险,筛选出淋巴结转移风险低的患者使其避免腋窝手术是否安全仍需相关的临床试验验证.
액와림파결전이상태시유선암환자최중요적예후결정인소지일.연합림상사체급초성、목파、CT、MRI、PET-CT등영상학검사가이제고예측준학솔,단잉존재교고적가음성솔.초성인도하세침천자액와림파결능유효제고술전진단솔.결합환자적림상병리특정,이용수학급통계학방법구건예측전초혹비전초림파결전이상태적모형가이계산기전이풍험,사선출림파결전이풍험저적환자사기피면액와수술시부안전잉수상관적림상시험험증.
Axillary lymph node status isone of the most important prognostic factors for the patients with breast cancer.Physical examination combining with ultrasound, mammography, CT, MRI and PET-CT can improve the predictive efficiency, but there is still high false negative rate.Ultrasound-guided fine-needle aspiration for axillary lymph node can improve preoperative diagnostic rate effectively.Using mathematical and statistical methods, building models for predicting sentinel lymph node or non-sentinel lymph node status with clinicopathological features helps to calculate the risk of lymph node involvement.Whether screening out patients with low risk of lymph node involvement avoiding axillary surgery is safe or not is still to be evaluated by relevant clinical trials.