miR-375在消化系统肿瘤中的表达及作用
miR-375재소화계통종류중적표체급작용
Expression and role of miRNA-375 in digestive system tumors
  • 万方数据
    国际肿瘤学杂志 국제종류학잡지
    Journal of International Oncology
    2015年 11期 863-865 ,共3页

    陈征%刘晓峰%董倩倩%麻树霖

    진정%류효봉%동천천%마수림

    微RNAs%消化系统肿瘤%肿瘤转移 微RNAs%消化繫統腫瘤%腫瘤轉移
    미RNAs%소화계통종류%종류전이
    MicroRNAs%Digestive system neoplasms%Neoplasm metastasis
    微小RNA通过调节基因转录后水平的表达在生物学过程发挥重要作用.越来越多的研究发现miR-375在消化系肿瘤中普遍低表达,与肿瘤的发生有关.过表达的miR-375可通过抑制靶基因的表达起到抑制肿瘤生长、转移的作用.
    미소RNA통과조절기인전록후수평적표체재생물학과정발휘중요작용.월래월다적연구발현miR-375재소화계종류중보편저표체,여종류적발생유관.과표체적miR-375가통과억제파기인적표체기도억제종류생장、전이적작용.
    micmRNA (miRNA) plays an important role in biological processes via regulating gene expression in the level of posttranscription.Increasing number of studies reveal that miR-375 is downregulated in digestive system tumors, and is related to tumorigenesis.Overexpression of miR-375 can inhibit growth and metastasis of tumors through repressing the expression of target genes.
    원문보기 원문다운로드 사이트로이동
저자의 최근 논문