CAJ | 학술논문

葫芦脲是超分子化学中继冠醚、环糊精、杯芳烃之后发展起来的又一类新型高度对称的桶状大环主体分子，是一种由多个甘脲单元组成的大环穴状配体，被誉为“第四代超分子化合物”。由于其具有特殊的分离选择性和稳定性，在超分子化学和色谱的交叉领域备受关注。本文从葫芦脲的结构特征出发，侧重概述了葫芦脲同系物及其衍生物在色谱固定相中的研究现状和进展。
호호뇨시초분자화학중계관미、배호정、배방경지후발전기래적우일류신형고도대칭적통상대배주체분자，시일충유다개감뇨단원조성적대배혈상배체，피예위“제사대초분자화합물”。유우기구유특수적분리선택성화은정성，재초분자화학화색보적교차영역비수관주。본문종호호뇨적결구특정출발，측중개술료호호뇨동계물급기연생물재색보고정상중적연구현상화진전。
Cucurbit[ n]urils( CB[ n]),a kind of host molecules of the fourth generation supramolecule followed crown ethers,cyclodextrins and calixarenes in supramolecular chemis-try,are macrocyclic ligands and consist of several glycoluril units. Their special molecular rec-ognition based on unique separation selectivity and stability have gained great interest in supra-molecular chemistry and chromatography. Hereby,we give a review of research progresses of cucurbit[ n]urils structural features,its homologues and derivatives and their applications in chromatographic stationary phase.