CAJ | 학술논문

本文采用电化学性能独特的联吡啶钌(Ru(bpy)32+)、氮掺杂石墨烯(NG)和Nafion膜构建了一种新型的盐酸异丙嗪电化学传感器。采用红外光谱和扫描电子显微镜对氮掺杂石墨烯的形貌进行了表征。在Na-fion膜中添加导电性好、比表面积大的氮掺杂石墨烯可以增加电子传递速度并且可以防止联吡啶钌扩散到Nafion膜的非电活性区域而增加电极使用寿命。在pH 7．0的磷酸盐缓冲溶液中，盐酸异丙嗪在Ru( bpy)32+/NG/Nafion修饰电极上的循环伏安曲线表明，与单一的裸玻碳电极、Ru(bpy)32+/ Nafion修饰电极以及NG/Na-fion修饰电极相比，该修饰电极使盐酸异丙嗪得氧化峰电流显著增加，而峰电位明显负移，表明采用 Ru ( bpy)32+/NG/Nafion膜制备的复合修饰电极对盐酸异丙嗪呈现出较强的电化学催化作用。优化实验条件后，发现在1．0×10-6 mol·L-1~1．0×10-4 mol·L-1．浓度范围内，盐酸异丙嗪的氧化峰电流与其浓度呈良好的线性关系，检测限为3．6×10-7mol·L-1。而且该电极的重现性、稳定性和选择性良好，采用标准加入法可成功用于商业盐酸异丙嗪注射液中盐酸异丙嗪的测定。
본문채용전화학성능독특적련필정조(Ru(bpy)32+)、담참잡석묵희(NG)화Nafion막구건료일충신형적염산이병진전화학전감기。채용홍외광보화소묘전자현미경대담참잡석묵희적형모진행료표정。재Na-fion막중첨가도전성호、비표면적대적담참잡석묵희가이증가전자전체속도병차가이방지련필정조확산도Nafion막적비전활성구역이증가전겁사용수명。재pH 7．0적린산염완충용액중，염산이병진재Ru( bpy)32+/NG/Nafion수식전겁상적순배복안곡선표명，여단일적라파탄전겁、Ru(bpy)32+/ Nafion수식전겁이급NG/Na-fion수식전겁상비，해수식전겁사염산이병진득양화봉전류현저증가，이봉전위명현부이，표명채용 Ru ( bpy)32+/NG/Nafion막제비적복합수식전겁대염산이병진정현출교강적전화학최화작용。우화실험조건후，발현재1．0×10-6 mol·L-1~1．0×10-4 mol·L-1．농도범위내，염산이병진적양화봉전류여기농도정량호적선성관계，검측한위3．6×10-7mol·L-1。이차해전겁적중현성、은정성화선택성량호，채용표준가입법가성공용우상업염산이병진주사액중염산이병진적측정。
A novel promethazine hydrochloride(PMZ)electrochemical sensor based on tris(2,2’-bipyridy)ruthenium(II)(Ru ( bpy) 3 2+) ,nitrogen dopedgraphene( NG) and Nafion composite film modified electrode was fabricated. The nitrogen dopedgraphene-was characterized by infrared? spectroscopy and scanning electron microscopy ( SEM ) . The introduction of conductive nitrogen doped graphene into can improve the electron transfer and the stability of the sensor by inhibiting the migration of Ru( bpy) 3 2+ into the electrochemically inactive hydrophobic region of Nafion. The electrochemical oxidation behavior of PMH was investigated in pH 7. 0 phosphate buffer solution by cyclicvoltammetry. It canbe foundthat the oxidation peak current of PMH increased significantly and the oxidation peak potential shifted negatively at Ru ( bpy ) 3 2+/NG/Nafion modified electrode compared with bare GCE, Ru ( bpy) 3 2+/Nafion modified electrode and NG/Nafion modified electrode,indicating that Ru( bpy) 3 2+/NG/Nafion modified electrode possessed electrocatalytic activity to PMZ. Under the optimal experimental conditions,the calibration curve for PMZ determination was obtained in the range of 1. 0×10-6 mol·L-1 to 1. 0×10-4 mol·L-1. The detection limit for PMZ was 3. 6×10-7mol·L-1. Moreover, the Ru( bpy) 3 2+/NG/Nafion modified electrode demonstrated excellent reproducibility,stability and selectivity. Using the proposed method,PMZ was successfully determined in commercial injections with standard addition method.