化学研究与应用
化學研究與應用
화학연구여응용
Chemical Research and Application
2015年
11期
1660-1665
,共6页
张茂美%龚军%周夏禹%荣春英%刘汉%涂冰
張茂美%龔軍%週夏禹%榮春英%劉漢%塗冰
장무미%공군%주하우%영춘영%류한%도빙
钯%炔碘化合物%交叉偶联%有机锡化合物%炔烃
鈀%炔碘化閤物%交扠偶聯%有機錫化閤物%炔烴
파%결전화합물%교차우련%유궤석화합물%결경
palladium%alkynyl iodides%cross-coupling reaction%organotin compounds%alkynes
以钯为催化剂,DMEDA为配体,实现了碱性条件下炔碘化合物与有机锡化合物的Stille交叉偶联反应,合成了一系列芳环上含有甲基、甲氧基及卤原子的中间炔烃。该方法底物适应范围广、产率高,为C—C键的构筑提供了一条新路径。
以鈀為催化劑,DMEDA為配體,實現瞭堿性條件下炔碘化閤物與有機錫化閤物的Stille交扠偶聯反應,閤成瞭一繫列芳環上含有甲基、甲氧基及滷原子的中間炔烴。該方法底物適應範圍廣、產率高,為C—C鍵的構築提供瞭一條新路徑。
이파위최화제,DMEDA위배체,실현료감성조건하결전화합물여유궤석화합물적Stille교차우련반응,합성료일계렬방배상함유갑기、갑양기급서원자적중간결경。해방법저물괄응범위엄、산솔고,위C—C건적구축제공료일조신로경。
Palladium-catalyzed Stille cross-coupling reaction of alkynyl iodides and organotin compounds was developed under alka-line conditions,with DMEDA as ligand,which synthesized a series of internal alkynes including Me,MeO and halogen functional groups on the aromatic ring. The method had advantages of wide range of substrates and high yields,which provided a new route for the construction of C—C bond.
