CAJ | 학술논문

目的：探讨联合应用肾上腺素和甲泼尼龙琥珀酸钠对心肺复苏（CPR）自主循环恢复的成功率及CPR后的存活率的影响。方法：随机抽取100例心跳停搏（心脏停搏）患者，将其分为治疗组（50例）及对照组（50例）。治疗组给予标准剂量肾上腺素、甲泼尼龙琥珀酸，对照组给予标准剂量肾上腺素。观察2组患者的自主循环恢复率及出院存活率。结果：治疗组自主循环恢复率及出院存活率分别为62．0％、14．0％，对照组自主循环恢复率及出院存活率分别为16．0％、4．0％，2组差异有统计学意义（P＜0．05）。结论：心肺复苏时联合应用肾上腺素与甲泼尼龙琥珀酸可显著提高自主循环恢复率及出院存活率。
목적：탐토연합응용신상선소화갑발니룡호박산납대심폐복소（CPR）자주순배회복적성공솔급CPR후적존활솔적영향。방법：수궤추취100례심도정박（심장정박）환자，장기분위치료조（50례）급대조조（50례）。치료조급여표준제량신상선소、갑발니룡호박산，대조조급여표준제량신상선소。관찰2조환자적자주순배회복솔급출원존활솔。결과：치료조자주순배회복솔급출원존활솔분별위62．0％、14．0％，대조조자주순배회복솔급출원존활솔분별위16．0％、4．0％，2조차이유통계학의의（P＜0．05）。결론：심폐복소시연합응용신상선소여갑발니룡호박산가현저제고자주순배회복솔급출원존활솔。
Objective:To explore whether the combination therapy of epinephrine and methylprednisolone during intrahospital cardiopulmonary resuscitation (CPR) could increase the rate of restoration of spontaneous circulation (ROSC) and improve the survival rate after CPR .Methods:One hundred patients with cardiac arrest were randomly recruited and allocated into therapy group(n=50) and control group(n=50) .Standard dose of epinephrine and methylprednisolone were applied in therapy group , while standard dose of methylprednisolone was applied in control group .The ROSC rate and post‐discharge survival rate of patients in both groups were observed .Results:The ROSC rate and post‐discharge survival rate in the therapy group were 62 .0% and 14 .0% ,respectively ,while that in the control group were 16 .0% and 4 .0% ,respectively .The differences between the two groups were statistically significant(P<0 .05) .Conclusions:Combination therapy of methylprednisolone and epinephrine during CPR could significantly improve the ROSC rate and post‐discharge survival rate .