中国临床医学
中國臨床醫學
중국림상의학
Chinese Journal of Clinical Medicine
2015年
5期
633-636
,共4页
慢性心力衰竭%肾功能不全%肾功能恶化%危险因素
慢性心力衰竭%腎功能不全%腎功能噁化%危險因素
만성심력쇠갈%신공능불전%신공능악화%위험인소
Chronic heart failure%Renal insufficiency%Worsening renal function%Risk factors
目的：观察慢性心力衰竭（chronic heart failure ，CHF）住院患者肾功能恶化的发生率和临床特点，并探讨CHF住院患者肾功能恶化的危险因素。方法：采用病例对照研究的方法，以住院期间血肌酐（Scr）的变化值判断CHF患者的肾功能是否恶化；采用logistic回归方程分析CHF患者肾功能恶化的独立危险因素。结果：中、重度CHF住院患者肾功能不全的发生率为38．21％，肾功能恶化的发生率为22．76％。贫血[血红蛋白（Hb）＜90 g／L ，P＝0．042]、低钠血症（Na＋＜135 mmol／L ，P＝0．019）、肾功能不全[肾小球滤过率（GFR）＜60 mL／（min ·1．73 m2），P＝0．001]与肾功能恶化的发生独立相关。结论：肾功能不全、贫血和低钠血症是CHF患者肾功能恶化的重要危险因素。
目的：觀察慢性心力衰竭（chronic heart failure ，CHF）住院患者腎功能噁化的髮生率和臨床特點，併探討CHF住院患者腎功能噁化的危險因素。方法：採用病例對照研究的方法，以住院期間血肌酐（Scr）的變化值判斷CHF患者的腎功能是否噁化；採用logistic迴歸方程分析CHF患者腎功能噁化的獨立危險因素。結果：中、重度CHF住院患者腎功能不全的髮生率為38．21％，腎功能噁化的髮生率為22．76％。貧血[血紅蛋白（Hb）＜90 g／L ，P＝0．042]、低鈉血癥（Na＋＜135 mmol／L ，P＝0．019）、腎功能不全[腎小毬濾過率（GFR）＜60 mL／（min ·1．73 m2），P＝0．001]與腎功能噁化的髮生獨立相關。結論：腎功能不全、貧血和低鈉血癥是CHF患者腎功能噁化的重要危險因素。
목적：관찰만성심력쇠갈（chronic heart failure ，CHF）주원환자신공능악화적발생솔화림상특점，병탐토CHF주원환자신공능악화적위험인소。방법：채용병례대조연구적방법，이주원기간혈기항（Scr）적변화치판단CHF환자적신공능시부악화；채용logistic회귀방정분석CHF환자신공능악화적독립위험인소。결과：중、중도CHF주원환자신공능불전적발생솔위38．21％，신공능악화적발생솔위22．76％。빈혈[혈홍단백（Hb）＜90 g／L ，P＝0．042]、저납혈증（Na＋＜135 mmol／L ，P＝0．019）、신공능불전[신소구려과솔（GFR）＜60 mL／（min ·1．73 m2），P＝0．001]여신공능악화적발생독립상관。결론：신공능불전、빈혈화저납혈증시CHF환자신공능악화적중요위험인소。
Objective:To observe the incidence rate and the clinical characteristics of worsening renal function in hospitalized patients with chronic heart failure (CHF) ,and explore the risk factors associated with worsening renal function in hospitalized CHF patients .Methods:By using case‐control method ,the changed value of serum creatinine (Scr) during hospitalization was evaluated to judge whether the renal function of CHF patients deteriorated .And the independent risk factors for worsening renal function in CHF patients were analyzed by logistic regression equation .Results:The incidence of renal insufficiency in hospitalized patients with medium and severe CHF was 38 .21% ,while the incidence of worsening renal function was 22 .76% . Anemia (Hb<90 g/L , P=0 .042) ,hyponatremia (Na+ <135 mmol/L , P=0 .019) ,and renal function insufficiency (GFR<60 mL/[min · 1 .73 m2 ] ,P=0 .001) was independently associated with the deterioration of renal function .Conclusions:The renal insufficiency ,anemia ,and hyponatremia are important risk factors for worsening renal function in CHF patients .
