CAJ | 학술논문

14日龄健康、非免疫罗曼蛋公鸡240只，随机均分为8组，用鸡新城疫疫苗首次免疫和二次免疫前3 d、当日及后3d，试验组分别灌胃0.5 ml高、低剂量黄芪多糖（ ASP）、淫羊藿多糖（EPP）和板蓝根多糖（IRPS）溶液，空白对照组和免疫对照组灌胃等量生理盐水。各组分别于首免后连续4周随机取鸡10只称量体重、测定抗体效价和 T淋巴细胞增殖变化。结果表明，3种中药多糖均可促进鸡只增重，提高新城疫 HI抗体效价，促进外周血 T淋巴细胞增殖，其中低剂量的 IRPS效果最好。
14일령건강、비면역라만단공계240지，수궤균분위8조，용계신성역역묘수차면역화이차면역전3 d、당일급후3d，시험조분별관위0.5 ml고、저제량황기다당（ ASP）、음양곽다당（EPP）화판람근다당（IRPS）용액，공백대조조화면역대조조관위등량생리염수。각조분별우수면후련속4주수궤취계10지칭량체중、측정항체효개화 T림파세포증식변화。결과표명，3충중약다당균가촉진계지증중，제고신성역 HI항체효개，촉진외주혈 T림파세포증식，기중저제량적 IRPS효과최호。
240 14-day-old healthy and non-immune Roman chicken were randomly divided into 8 groups, including blank control group (BC group), immune control group (IC group), and immunity groups of each Chinese medicine. On the day of the first immunity, 3 d before the second immunity, the day of the second immunity and 3 d after the second immunity, high-dose concentration and low-dose concen-tration of Astragalus polysaccharide (ASP), Epimedium polysaccharide (EPP) and Isatis roots polysaccharide (IRPS) were used for the immunity groups of each Chi-nese medicine using the gavage, and 0.5 ml for each chick, and the equivalent normal saline was used for the blank control group and vaccine control group. On the 7th, 14th, 21st and 28th day after the first immunity, 10 chicken of each group were randomly got and weighed, and the antibody titer and the changes of the pro-liferation of T lymphocyte were measured. The results showed that 3 kinds of Chi-nese medicine polysaccharides al can increase the weight of chicken, improve HI antibody titer of Newcastle disease, and promote the proliferation of peripheral T lymphocyte, in which the effect of IRPS at low dosage is the best.