CAJ | 학술논문

目的：探讨新活素对急性前壁心肌梗死急诊介入术后心力衰竭患者治疗效果。方法：选取2013年2月~2015年2月某院收治128例前壁心肌梗死介入术后心力衰竭患者随机分为观察组和对照组,观察组在常规治疗基础上给予新活素,对照组给予硝酸甘油,比较两组患者治疗36 h后疗效、肾素、血管紧张素Ⅱ、醛固酮及左心室舒张末期容积(LVEDV)、左心室射血分数(LVEF)及尿量。结果：观察组治疗效果显著于对照组[96.87%比84.38%,P<0.05]。观察组肾素、血管紧张素Ⅱ、醛固酮水平均低于对照组[(7.3±2.1)ng/L比(8.4±2.2)ng/L,(153.3±32.2)ng/L比(178.5±38.4)ng/L,(92.1±12.5)ng/L比(99.5±15.3)ng/L,P<0.05]。观察组 LVEDV低于对照组,LVEF及尿量高于对照组[(142.1±16.4)mm 比(149.9±16.8)mm,(63.1±11.0)%比(58.4±10.1)%,(66.9±11.8)ml/L比(56.8±10.6)ml/L,P<0.05]。结论：新活素治疗急性前壁心肌梗死急诊介入术后心力衰竭可有效改善患者心功能,提高治疗效果。
목적：탐토신활소대급성전벽심기경사급진개입술후심력쇠갈환자치료효과。방법：선취2013년2월~2015년2월모원수치128례전벽심기경사개입술후심력쇠갈환자수궤분위관찰조화대조조,관찰조재상규치료기출상급여신활소,대조조급여초산감유,비교량조환자치료36 h후료효、신소、혈관긴장소Ⅱ、철고동급좌심실서장말기용적(LVEDV)、좌심실사혈분수(LVEF)급뇨량。결과：관찰조치료효과현저우대조조[96.87%비84.38%,P<0.05]。관찰조신소、혈관긴장소Ⅱ、철고동수평균저우대조조[(7.3±2.1)ng/L비(8.4±2.2)ng/L,(153.3±32.2)ng/L비(178.5±38.4)ng/L,(92.1±12.5)ng/L비(99.5±15.3)ng/L,P<0.05]。관찰조 LVEDV저우대조조,LVEF급뇨량고우대조조[(142.1±16.4)mm 비(149.9±16.8)mm,(63.1±11.0)%비(58.4±10.1)%,(66.9±11.8)ml/L비(56.8±10.6)ml/L,P<0.05]。결론：신활소치료급성전벽심기경사급진개입술후심력쇠갈가유효개선환자심공능,제고치료효과。
Objective:To investigate the therapeutic effect of new bios for acute anterior myocardial infarc-tion patients with heart failure after the intervention of Emergency.Methods:Select 128 cases of anterior my-ocardial infarction,heart failure patients after interventional February 2013-February 2015 in some hospi-tal,randomly divide them to observation group and control group,the observation group were new active el-ement in conventional therapy,the control group was given nitroglycerin,compare the two groups of pa-tients after 36h,efficacy,renin,angiotensin Ⅱ,aldosterone and left ventricular end-diastolic volume (LV-EDV),left ventricular ej ection fraction (LVEF)and urine.Results:Treatment effect was observed in the control group was significantly [96.87% vs.84.38%,P<0.05].Renin,angiotensin Ⅱ,aldosterone levels in the observation group were lower than those in the control group [(7.3 ± 2.1)ng/L vs.(8.4 ± 2.2)ng/L,(153.3 ± 32.2)ng/L vs.(178.5 ± 38.4)ng/L,(92.1 ± 12.5)ng/L vs.(99.5 ± 15.3)ng/L,P<0.05].LVEDV observation group than the control group,LVEF and urine output higher than [(142.1 ± 16. 4)mm vs.(149.9 ± 16.8)mm,(63.1 ± 11.0)% vs.(58.4 ± 10.1)%,(66.9 ± 11.8)ml/L vs.(56.8 ± 10.6)ml/L,P<0.05].Conclusion:New Cytokines the treatment of acute myocardial infarction heart failure after EMERGENCY intervention can improve heart function,improve the therapeutic effect.