国际医学放射学杂志
國際醫學放射學雜誌
국제의학방사학잡지
International Journal of Medical Radiology
2015年
6期
544-547
,共4页
癌症筛查%低剂量CT%肺癌%微小核糖核酸%风险因素
癌癥篩查%低劑量CT%肺癌%微小覈糖覈痠%風險因素
암증사사%저제량CT%폐암%미소핵당핵산%풍험인소
Cancer screening%Low-dose CT%Lung cancer%Micro RNAs%Risk factor
肺癌是全球范围内死亡率最高的肿瘤,早期诊断对肺癌的预后至关重要。研究显示运用低剂量CT (LDCT)进行肺癌筛查可使肺癌的死亡率显著下降,因此肺癌筛查成为肿瘤防治方面的新热点。在关注LDCT效果的同时,其存在的问题亦不可忽视,如过高的假阳性率、高危人群和风险模型的确立、过度诊断、辐射效应等。就肺癌筛查存在的问题和研究进展进行综述。
肺癌是全毬範圍內死亡率最高的腫瘤,早期診斷對肺癌的預後至關重要。研究顯示運用低劑量CT (LDCT)進行肺癌篩查可使肺癌的死亡率顯著下降,因此肺癌篩查成為腫瘤防治方麵的新熱點。在關註LDCT效果的同時,其存在的問題亦不可忽視,如過高的假暘性率、高危人群和風險模型的確立、過度診斷、輻射效應等。就肺癌篩查存在的問題和研究進展進行綜述。
폐암시전구범위내사망솔최고적종류,조기진단대폐암적예후지관중요。연구현시운용저제량CT (LDCT)진행폐암사사가사폐암적사망솔현저하강,인차폐암사사성위종류방치방면적신열점。재관주LDCT효과적동시,기존재적문제역불가홀시,여과고적가양성솔、고위인군화풍험모형적학립、과도진단、복사효응등。취폐암사사존재적문제화연구진전진행종술。
Lung cancer has become the leading cause of cancer mortality globally. Early diagnosis is important for the good prognosis. Evidence has shown low-dose CT screening can significantly decrease the mortality of lung cancer , the lung cancer screening has become a new research focus recently. However, in spite of the advantage, there are still many problems in the screening, such as, high false-positive rates, problem in establishing accurate risk prediction model, overdiagnosis, and radiation exposure. We reviewed the existing problems and research development of lung cancer screening.