CAJ | 학술논문

阿尔茨海默病（AD）是一种以进行性认知障碍和行为异常为主要表现的神经退行性疾病。早期神经放射学多采用结构MRI研究AD 局部脑区的改变，随着多模态MRI 的发展，研究者们从功能连接、代谢水平、白质纤维成像、血流动力学等方面对AD进一步评价，从而为AD的临床诊断、分期、治疗和预后提供了放射学依据。就多模态MRI技术在AD中的研究进展予以综述。
아이자해묵병（AD）시일충이진행성인지장애화행위이상위주요표현적신경퇴행성질병。조기신경방사학다채용결구MRI연구AD 국부뇌구적개변，수착다모태MRI 적발전，연구자문종공능련접、대사수평、백질섬유성상、혈류동역학등방면대AD진일보평개，종이위AD적림상진단、분기、치료화예후제공료방사학의거。취다모태MRI기술재AD중적연구진전여이종술。
Alzheimer’s disease (AD) is a nervous degenerative disease characterized by progressive cognitive disability and behavior deficits. Previous neuroradiology investigated the regional brain change of AD usually by applying structural MRI. With development of multimodality MRI techniques, researchers can evaluated AD in terms of functional connectivity, metabolism level, white mater fiber track, hemodynamics. Meanwhile, multimodality MRI can offer radiological evidences for clinical diagnosis, staging, treatment and prognosis. We reviewed the research progress of multimodality MRI techniques in AD.