中国民族民间医药
中國民族民間醫藥
중국민족민간의약
Chinese Journal of Ethnomedicine and Ethnopharmacy
2015年
21期
11-13
,共3页
定痛宁颗粒%挥发油%包合工艺
定痛寧顆粒%揮髮油%包閤工藝
정통저과립%휘발유%포합공예
Dingtongning Granule%Volatile Oil%Inclusion Design
目的：优选定痛宁颗粒中川芎与细辛挥发油的提取和包合工艺。方法：采用 L9（34）正交试验法，以挥发油提取量为指标，优选挥发油的提取工艺；以包合物收得率和挥发油包合率为指标，优选β－环糊精（β－CD）的包合工艺。结果：挥发油提取最佳工艺为：加8倍量水，浸泡1h，提取6h；包合最佳工艺为：挥发油∶采用饱和水溶液法，β－CD 为1∶8，在50℃包合1.5h，包合温度为。结论：优选的挥发油提取及包合工艺稳定可行。
目的：優選定痛寧顆粒中川芎與細辛揮髮油的提取和包閤工藝。方法：採用 L9（34）正交試驗法，以揮髮油提取量為指標，優選揮髮油的提取工藝；以包閤物收得率和揮髮油包閤率為指標，優選β－環糊精（β－CD）的包閤工藝。結果：揮髮油提取最佳工藝為：加8倍量水，浸泡1h，提取6h；包閤最佳工藝為：揮髮油∶採用飽和水溶液法，β－CD 為1∶8，在50℃包閤1.5h，包閤溫度為。結論：優選的揮髮油提取及包閤工藝穩定可行。
목적：우선정통저과립중천궁여세신휘발유적제취화포합공예。방법：채용 L9（34）정교시험법，이휘발유제취량위지표，우선휘발유적제취공예；이포합물수득솔화휘발유포합솔위지표，우선β－배호정（β－CD）적포합공예。결과：휘발유제취최가공예위：가8배량수，침포1h，제취6h；포합최가공예위：휘발유∶채용포화수용액법，β－CD 위1∶8，재50℃포합1.5h，포합온도위。결론：우선적휘발유제취급포합공예은정가행。
Objective To optimize the extraction and inclusion condition of volatile oil from Chuanxiong and Xixin in Dingtongning granule.Methods By orthogonal design of L9 (34 ),the study were carried out with orthogonal experiment.With the volume of vola-tile oil as the target markers,the optimum conditions were determined for extraction of the volatile oil.With the recovery rate of inclu-sion and the volatile oil inclusion rate as the target marker the conditions for including the oil were optimized.Results The optimized extraction conditions were:the water was 8 times,the medical material should be extracted for 6h with soaking 1.5 h.The optimal in-clusion conditions were:applying the saturated aqueous solution method,the oil and proportion ofβ-CD was8∶1,temperature was 50℃ for inclusion,and the time was1.5 h.Conclusion:The optimum conditions for extra -ction and inclusion are steady and feasi-ble.
