CAJ | 학술논문

综述了近年来对排放到环境中药物的研究进展. 从药物生产、药物使用、过期和剩余药物处理等环节阐述了药物的来源;介绍了药物的检测技术,包括样品提取净化技术、色谱分离技术以及色谱质谱联用技术;分析了环境中药物的归趋方式,包括吸附、生物降解、水解和光降解等途径;阐释了环境中药物对环境生物体的急性、慢性毒性,以及多种药物对生物体复合毒性对环境的影响.
종술료근년래대배방도배경중약물적연구진전. 종약물생산、약물사용、과기화잉여약물처리등배절천술료약물적래원;개소료약물적검측기술,포괄양품제취정화기술、색보분리기술이급색보질보련용기술;분석료배경중약물적귀추방식,포괄흡부、생물강해、수해화광강해등도경;천석료배경중약물대배경생물체적급성、만성독성,이급다충약물대생물체복합독성대배경적영향.
The present research status of pharmaceuticals in the environment was summarized.The source of pharmaceuticals released to the environment, including drug production, drug use and disposal of excess and outdated pills was elaborated.The detecting methods of pharmaceuticals, involving sample extraction and purifying, chromatographic separation, and chromatography-mass spectrometry, were introduced.The fate of pharmaceuticals in the environment, including the ways of absorption, biodegradation, hydrolysis and photodegradation, was introduced. The environmental impact was illustrated from the findings of chronic and acute effects of pharmaceuticals in laboratory and environment experiments and the complex effects on organism of muti-component pharmaceutical mixtures.