CAJ | 학술논문

目的：研究中药脉血康胶囊对不稳定型心绞痛患者症状及血液流变学的影响。方法：将105例不稳定型心绞痛患者随机均分为综合组及对照组。两组患者均采用常规治疗方案，包括口服辛伐他汀、拜阿司匹灵及硝酸异山梨酯。综合组在此基础上加用脉血康胶囊。两组患者均治疗1个月后评价治疗前后症状改善及血液流变学变化。结果：在症状上，两组患者治疗后心绞痛发作频率、心绞痛持续时间、心电图ST段压低数及T波总倒置数明显低于治疗前（P<0.01），而治疗后综合组患者在症状的四个指标方面均明显低于对照组（P<0.01）；在血液流变学上，两组患者治疗后全血黏度（低切、高切）、血浆黏度及红细胞聚变指数均明显低于治疗前（P<0.01），而治疗后综合组患者血液流变学四个指标均明显低于对照组（P<0.01）。结论：脉血康胶囊具有改善不稳定型心绞痛患者血液浓、黏、聚状态，降低心绞痛发作频率及持续时间，增强心肌供血的作用。
목적：연구중약맥혈강효낭대불은정형심교통환자증상급혈액류변학적영향。방법：장105례불은정형심교통환자수궤균분위종합조급대조조。량조환자균채용상규치료방안，포괄구복신벌타정、배아사필령급초산이산리지。종합조재차기출상가용맥혈강효낭。량조환자균치료1개월후평개치료전후증상개선급혈액류변학변화。결과：재증상상，량조환자치료후심교통발작빈솔、심교통지속시간、심전도ST단압저수급T파총도치수명현저우치료전（P<0.01），이치료후종합조환자재증상적사개지표방면균명현저우대조조（P<0.01）；재혈액류변학상，량조환자치료후전혈점도（저절、고절）、혈장점도급홍세포취변지수균명현저우치료전（P<0.01），이치료후종합조환자혈액류변학사개지표균명현저우대조조（P<0.01）。결론：맥혈강효낭구유개선불은정형심교통환자혈액농、점、취상태，강저심교통발작빈솔급지속시간，증강심기공혈적작용。
Objective: To observe effects of the Maixuekang capsules on unstable angina and hemorheology. Methods: 105 cases were randomly divided into the integrated group and the control group. They took conventional treatment. The integrated group took the Maixuekang capsules more. Results: After treatment, angina frequency, duration of angina, ST segment depression and T-wave total inversion number were significantly lower than before (P<0.01); in the integrated group, four indicators of the symptoms were significantly lower (P<0.01). After treatment, in the rheology, whole blood viscosity (low-cut, high-cut), plasma viscosity and erythrocyte fusion index were significantly lower than before (P<0.01); in the integrated group, four indicators of hemrheology were significantly lower (P<0.01). Conclusion: The Maixuekang capsules can improve blood thick, sticky, polyethylene status, reduce the frequency and duration of angina attack, and enhance myocardial blood supply.