中医临床研究
中醫臨床研究
중의림상연구
Clinical Journal of Chinese Medicine
2015年
29期
6-9
,共4页
溃疡性结肠炎%健脾涩肠汤%口服灌肠%临床观察
潰瘍性結腸炎%健脾澀腸湯%口服灌腸%臨床觀察
궤양성결장염%건비삽장탕%구복관장%림상관찰
Chronic ulcerative colitis%The Jianpi Sechang decoction%Oral and enema%Clinical observation
目的：探讨自拟健脾涩肠汤口服灌肠给药治疗慢性溃疡性结肠炎的临床疗效。方法：治疗组30例，采用自拟健脾涩肠汤水煎，口服加灌肠给药；对照组30例口服美沙拉嗪肠溶片和双歧杆菌三联活菌胶囊，同时给予美沙拉嗪肠溶片灌肠。两组分别治疗8周，做疗效对比，对疗效显著患者随访6个月，观察其复发情况。结果：中医临床证候疗效：治疗组总有效率为90.0%，对照组总有效率为76.7%；治疗后结肠黏膜病变：治疗组总有效率为90.0%，对照组总有效率为83.3%；临床综合疗效：治疗组总有效率为86.7%，对照组总有效率为73.3%；两组复发率比较，治疗组为11.1%，对照组为50.0%。两组在以上项目上比较均有显著性差异（P<0.05）。结论：健脾涩肠口服灌肠给药治疗脾胃气虚兼有瘀血阻滞型溃疡性结肠炎疗效确切，较少复发。
目的：探討自擬健脾澀腸湯口服灌腸給藥治療慢性潰瘍性結腸炎的臨床療效。方法：治療組30例，採用自擬健脾澀腸湯水煎，口服加灌腸給藥；對照組30例口服美沙拉嗪腸溶片和雙歧桿菌三聯活菌膠囊，同時給予美沙拉嗪腸溶片灌腸。兩組分彆治療8週，做療效對比，對療效顯著患者隨訪6箇月，觀察其複髮情況。結果：中醫臨床證候療效：治療組總有效率為90.0%，對照組總有效率為76.7%；治療後結腸黏膜病變：治療組總有效率為90.0%，對照組總有效率為83.3%；臨床綜閤療效：治療組總有效率為86.7%，對照組總有效率為73.3%；兩組複髮率比較，治療組為11.1%，對照組為50.0%。兩組在以上項目上比較均有顯著性差異（P<0.05）。結論：健脾澀腸口服灌腸給藥治療脾胃氣虛兼有瘀血阻滯型潰瘍性結腸炎療效確切，較少複髮。
목적：탐토자의건비삽장탕구복관장급약치료만성궤양성결장염적림상료효。방법：치료조30례，채용자의건비삽장탕수전，구복가관장급약；대조조30례구복미사랍진장용편화쌍기간균삼련활균효낭，동시급여미사랍진장용편관장。량조분별치료8주，주료효대비，대료효현저환자수방6개월，관찰기복발정황。결과：중의림상증후료효：치료조총유효솔위90.0%，대조조총유효솔위76.7%；치료후결장점막병변：치료조총유효솔위90.0%，대조조총유효솔위83.3%；림상종합료효：치료조총유효솔위86.7%，대조조총유효솔위73.3%；량조복발솔비교，치료조위11.1%，대조조위50.0%。량조재이상항목상비교균유현저성차이（P<0.05）。결론：건비삽장구복관장급약치료비위기허겸유어혈조체형궤양성결장염료효학절，교소복발。
Objective: To investigate clinical efficacy of the Jianpi Sechang decoction on chronic ulcerative colitis. Methods: 30 cases in the treatment group were given the Jianpi Sechang decoction, by oral and enema. 30 cases in the control group were given Mesalamine enteric-coated tablets by oral and enema, triple viable Bifidobacterium capsules by oral. In 8 weeks, the efficiency in two groups was compared. Patients with significant effects were followed up for 6 months, and recurrence was observed. Results: TCM clinical efficacy symptoms: the total efficiency was 90% in the treatment group, and 76.7% in the control group. The efficacy of colonic mucosa lesions: after the treatment, the total efficiency was 90% in the treatment group, and 83.3% in the control group. Comprehensive clinical efficacy: the total efficiency was 86.7% in the treatment group, and 73.3% in the control group. Recurrence rate was 11.1% in the treatment group, and 50.0% in the control group. The difference was statistically significant (P<0.05). Conclusion: The Jianpi Sechang decoction on chronic ulcerative colitis shows a significant effect, with less recurrence.
