检验医学与临床
檢驗醫學與臨床
검험의학여림상
Laboratory Medicine and Clinic
2015年
22期
3354-3356
,共3页
吴晓娟%彭方亮%周晓%郑姣妮
吳曉娟%彭方亮%週曉%鄭姣妮
오효연%팽방량%주효%정교니
计划性剖宫产%头孢唑林%头孢替安
計劃性剖宮產%頭孢唑林%頭孢替安
계화성부궁산%두포서림%두포체안
planned cesarean section%cefamezin%cefotiam
目的：探讨计划性剖宫产预防抗生素合理应用方案。方法2013年7月至2014年6月的计划性剖宫产200例分为观察组和对照组，每组100例，观察组将注射用头孢唑林钠1．0 g溶于生理盐水100 m L中于断脐后一次静脉滴注；对照组注射用头孢替安1．0g溶于生理盐水100mL中静脉滴注，首剂始于术前0．5h，每日2次，连用2d，观察术后两组体温、产褥病率、切口感染、子宫感染、呼吸泌尿系统感染发生及费用情况。结果两组术后最高体温、产褥病率、切口感染、子宫感染、呼吸泌尿系统感染率差异无统计学意义（均 P＞0．05）。但观察组抗生素费用明显少于对照组，差异有统计学意义（P＜0．05）。结论计划性剖宫产使用头孢菌素第1代断脐后单次给药是一种合理、有效、经济的方案。
目的：探討計劃性剖宮產預防抗生素閤理應用方案。方法2013年7月至2014年6月的計劃性剖宮產200例分為觀察組和對照組，每組100例，觀察組將註射用頭孢唑林鈉1．0 g溶于生理鹽水100 m L中于斷臍後一次靜脈滴註；對照組註射用頭孢替安1．0g溶于生理鹽水100mL中靜脈滴註，首劑始于術前0．5h，每日2次，連用2d，觀察術後兩組體溫、產褥病率、切口感染、子宮感染、呼吸泌尿繫統感染髮生及費用情況。結果兩組術後最高體溫、產褥病率、切口感染、子宮感染、呼吸泌尿繫統感染率差異無統計學意義（均 P＞0．05）。但觀察組抗生素費用明顯少于對照組，差異有統計學意義（P＜0．05）。結論計劃性剖宮產使用頭孢菌素第1代斷臍後單次給藥是一種閤理、有效、經濟的方案。
목적：탐토계화성부궁산예방항생소합리응용방안。방법2013년7월지2014년6월적계화성부궁산200례분위관찰조화대조조，매조100례，관찰조장주사용두포서림납1．0 g용우생리염수100 m L중우단제후일차정맥적주；대조조주사용두포체안1．0g용우생리염수100mL중정맥적주，수제시우술전0．5h，매일2차，련용2d，관찰술후량조체온、산욕병솔、절구감염、자궁감염、호흡비뇨계통감염발생급비용정황。결과량조술후최고체온、산욕병솔、절구감염、자궁감염、호흡비뇨계통감염솔차이무통계학의의（균 P＞0．05）。단관찰조항생소비용명현소우대조조，차이유통계학의의（P＜0．05）。결론계화성부궁산사용두포균소제1대단제후단차급약시일충합리、유효、경제적방안。
Objective To discuss the rational application scheme of prophylactic antibiotic use in planned ce‐sarean section .Methods 200 cases of planned cesarean section from July 2013 to June 2014 were divided into the ob‐servation group and the control group ,100 cases in each group .The observation group was given cefamezin 1g dissol‐ving in normal saline 100 mL by once intravenous drip immediately after cutting off the umbilical cord .The control group was given cefotiam 1 .0 g dissolving in normal saline 100 mL by intravenous drip ,the initial dose was given at preoperative 30 min ,twice a day for consecutive 2 d .The body temperature ,puerperal morbidity ,incision infection ,u‐terine infection ,respiratory and urogenital system infection and costs were compared between the two groups .Results The highest body temperature ,puerperal morbidity ,incision infection ,uterine infection ,respiratory and urogenital system infection after operation had no statistical differences between the two groups(P>0 .05) .The antibiotic cost of the observation group was significantly less than that of the control group ,and the difference was statistically sig‐nificant(P<0 .05) .Conclusion The single‐dose application of first generation cephalosporin after cutting off the um‐bilical cord for planned cesarean section can be regarded as a kind of reasonable ,effective and economical scheme .
