CAJ | 학술논문

目的：探讨血栓弹力图（T EG ）在急性脑梗死患者凝血方面的应用价值。方法采用全血复钙法对57例急性脑梗死患者治疗前后行T EG、常规凝血指标检查，并与健康对照组对比分析。结果与健康对照组比较，急性脑梗死治疗前患者的R值和K值明显缩短，α角、最大血块强度（MA）值、血凝块强度（G）、综合凝血指数（CI）和MA后30 min血凝块减少速率（LY30）增大，常规凝血参数水平的凝血酶原时间（PT）、PT‐国际标准化比值（INR）、活化部分凝血活酶时间（APTT）降低，纤维蛋白原（FIB）、D‐二聚体（D‐D）水平和血小板聚集试验（PAgT）明显升高，差异均有统计学意义（P＜0．05）。与急性脑梗死治疗前比较，治疗后患者的 TEG参数、常规凝血指标水平差异均有统计学意义（P＜0．05）。结论 TEG在监测急性脑梗死患者凝血、指导与监测药物治疗和评估患者预后具有较高的临床应用价值。
목적：탐토혈전탄력도（T EG ）재급성뇌경사환자응혈방면적응용개치。방법채용전혈복개법대57례급성뇌경사환자치료전후행T EG、상규응혈지표검사，병여건강대조조대비분석。결과여건강대조조비교，급성뇌경사치료전환자적R치화K치명현축단，α각、최대혈괴강도（MA）치、혈응괴강도（G）、종합응혈지수（CI）화MA후30 min혈응괴감소속솔（LY30）증대，상규응혈삼수수평적응혈매원시간（PT）、PT‐국제표준화비치（INR）、활화부분응혈활매시간（APTT）강저，섬유단백원（FIB）、D‐이취체（D‐D）수평화혈소판취집시험（PAgT）명현승고，차이균유통계학의의（P＜0．05）。여급성뇌경사치료전비교，치료후환자적 TEG삼수、상규응혈지표수평차이균유통계학의의（P＜0．05）。결론 TEG재감측급성뇌경사환자응혈、지도여감측약물치료화평고환자예후구유교고적림상응용개치。
Objective To investigate the application value of thrombelastography (TEG) in the coagulation monitoring among the patients with acute cerebral infarction .Methods TEG and conventional coagulation indicators detection were performed before and after treatment in 57 patients with acute cerebral infarction .The detection re‐sults were compared with those in the healthy control group .Results Compared with the healthy control group ,the R value and K value before treatment in the acute cerebral infarction group were significantly shortened ,theαangle , G ,MA value ,CI value and LY30 were significantly increased ,and PT ,PT‐INR and APTT were significantly de‐creased ,while the FIB ,D‐D levels and PAgT were significantly increased ,the differences were statistically significant (P<0 .05) .The parameters of TEG and levels of conventional coagulation indicators in the acute cerebral infarction group had statistically significantly differences between before and after treatment(P<0 .05) .Conclusion TEG has a higher clinical application value in monitoring the coagulation ,guiding and monitoring the medication therapy and e‐valuating the prognosis in the patients with acute cerebral infarction .