CAJ | 학술논문

在细胞膜中存在由胆固醇、鞘糖脂以及蛋白质等成分组成的液态有序的结构,叫做脂筏.从内质网到高尔基体再到细胞质膜,脂筏结构在细胞膜中所占的比例越来越高.脂筏在高尔基体到细胞质膜的物质转运以及细胞内吞、再循环过程中发挥着重要的作用.本文将就脂筏结构在物质从高尔基体到质膜的转运和细胞内吞过程中的作用及其分子机制做一综述.
재세포막중존재유담고순、초당지이급단백질등성분조성적액태유서적결구,규주지벌.종내질망도고이기체재도세포질막,지벌결구재세포막중소점적비례월래월고.지벌재고이기체도세포질막적물질전운이급세포내탄、재순배과정중발휘착중요적작용.본문장취지벌결구재물질종고이기체도질막적전운화세포내탄과정중적작용급기분자궤제주일종술.
The ordered liquid structure composed of cholesterol, glycosphingolipid and protein in cell mem-brane is called lipid raft. The proportion of lipid raft in cell membrane becomes higher from endoplasmic reticulum to Golgi apparatus and then to plasma membrane. Lipid raft plays an important role in the protein transport from Golgi apparatus to plasma membrane, in endocytosis and recycling. This review will focus on the function and molecular mechanism of lipid raft in the protein transport from Golgi apparatus to plasma membrane and endocytosis.