CAJ | 학술논문

目的：对前列地尔与贝那普利联合运用在糖尿病肾病蛋白尿的临床治疗效果进行探讨。方法选取该科2014年1月—2015年1月所收治的76例糖尿病肾病患者作为研究对象，全部患者均出现蛋白尿，按随机数字表法均分成实验组与对照组，对照组予以前列地尔治疗，在此基础之上，对实验组患者再予以贝那普利治疗，且对2组患者的治疗效果加以观察与比较。结果实验组患者治疗后的24 hUAE、24 h尿蛋白优于对照组治疗后，差异有统计学意义（P＜0.05）；实验组患者的总有效率（94.7%）比对照组患者（73.7%）高，差异有统计学意义（P＜0.05）。结论对糖尿病肾病患者予以前列地尔、贝那普利联合治疗，效果确切，不良反应少，且可有效改善患者的蛋白尿，值得在临床上推行。
목적：대전렬지이여패나보리연합운용재당뇨병신병단백뇨적림상치료효과진행탐토。방법선취해과2014년1월—2015년1월소수치적76례당뇨병신병환자작위연구대상，전부환자균출현단백뇨，안수궤수자표법균분성실험조여대조조，대조조여이전렬지이치료，재차기출지상，대실험조환자재여이패나보리치료，차대2조환자적치료효과가이관찰여비교。결과실험조환자치료후적24 hUAE、24 h뇨단백우우대조조치료후，차이유통계학의의（P＜0.05）；실험조환자적총유효솔（94.7%）비대조조환자（73.7%）고，차이유통계학의의（P＜0.05）。결론대당뇨병신병환자여이전렬지이、패나보리연합치료，효과학절，불량반응소，차가유효개선환자적단백뇨，치득재림상상추행。
Objective The alprostadil and Benner Pury combined with clinical therapeutic effect on diabetic nephropathy were discussed. Methods Select our department 2014 January to 76 cases of diabetic nephropathy patients in January 2015 are treated as the object of study. All the patients had proteinuria, according to the random number table method were randomly divided into experimental group and control group, control group treated with alprostadil treatment, on the basis of this, the patients in the experimental group and then be benazepril treatment and the therapeutic effect of two groups of patients be observation and comparison. Results After treatment, the 24 hUAE and 24 h urine protein in the experimental group was significantly higher than that in the control group ( P<0 . 05 ); the total effective rate of the experimental group (73.7%) was higher than that in the control group (P<0.05). Conclusion In patients with diabetic nephropathy be alprostadil, combined with benazepril in treatment, the exact effect, adverse reactions less and effectively improve the patients with proteinuria, worth in clinical implementation.