CAJ | 학술논문

目的：分析前列地尔治疗高龄糖尿病并慢性肾脏病患者疗效。方法回顾性分析该院2014年6月—2015年6月收治的128例高龄糖尿病并慢性肾脏病患者临床资料，根据不同治疗方案分为两组，对照组（70例）予以常规治疗，研究组（58例）于对照组基础上予以前列地尔治疗，观察并比较两组临床疗效、治疗前后的肾功能指标变化及不良反应情况。结果研究组治疗总有效率94.83%比对照组70.00%高，且Cr、24hUAER、Cys C及Ccr指标改善幅度显著大于对照组，均差异有统计学意义（P＜0.05）；研究组不良反应总发生率25.86%比对照组18.57%略高，差异无统计学意义（P＞0.05）。结论前列地尔治疗高龄糖尿病并慢性肾脏病患者疗效显著，可有效改善患者临床症状，降低蛋白尿，且安全性高，值得临床推广及应用。
목적：분석전렬지이치료고령당뇨병병만성신장병환자료효。방법회고성분석해원2014년6월—2015년6월수치적128례고령당뇨병병만성신장병환자림상자료，근거불동치료방안분위량조，대조조（70례）여이상규치료，연구조（58례）우대조조기출상여이전렬지이치료，관찰병비교량조림상료효、치료전후적신공능지표변화급불량반응정황。결과연구조치료총유효솔94.83%비대조조70.00%고，차Cr、24hUAER、Cys C급Ccr지표개선폭도현저대우대조조，균차이유통계학의의（P＜0.05）；연구조불량반응총발생솔25.86%비대조조18.57%략고，차이무통계학의의（P＞0.05）。결론전렬지이치료고령당뇨병병만성신장병환자료효현저，가유효개선환자림상증상，강저단백뇨，차안전성고，치득림상추엄급응용。
Objective To analyze the front to the treatment of elderly patients with diabetes and chronic kidney disease (CKD). Methods A retrospective analysis in June 2014 -June 2015 treated 128 cases of elderly patients with diabetes and chronic kidney disease (CKD) clinical data, according to the different treatments are divided into two groups, control group (70 cases) to conventional treatment, research group (58 cases) in the control group based on to the front to treatment, to ob-serve and compare the two groups of clinical curative effect, changes of renal function indexes before and after treatment, and adverse reactions. Results Treatment group total effective rate was 94.83% higher than the control group 70.00%, 24 huaer, Cys C and Cr, and Ccr index improvement was significantly greater than the control group, were statistically signifi-cant (P<0.05); Team of adverse reactions to the total incidence of 25.86% than the control group 18.57% slightly tall, not shown height difference (P>0.05). Conclusion Front row, diabetes and chronic kidney disease (CKD) in aged patients with obvious therapeutic effect, can effectively improve the patients' clinical symptoms, reduce proteinuria, and high safety, wor-thy of clinical popularization and application.