CAJ | 학술논문

目的：探讨促性腺激素释放激素激动剂（GnRH －a）联合左炔诺孕酮宫内缓释系统（LNG －IUS）对子宫内膜异位症Ⅲ－Ⅳ期患者术后疼痛的治疗效果。方法：回顾性分析100例已行保守性腹腔镜手术的子宫内膜异位症Ⅲ－Ⅳ期患者，给予 GnRH －a 联合 LNG －IUS 治疗的患者50例（实验组）；给予单纯 GnRH －a 治疗的患者50例（对照组）。术后6个月、12个月随访患者疼痛评分（VAS 法，B＆B 法）。结果：两组内术后6个月、12个月 VAS、B＆B 评分显著低于术前（P ＜0．05）。对照组术后12个月 VAS、B＆B 评分显著高于术后6个月（P ＜0．05）。实验组术后12个月 VAS、B＆B 评分显著低于对照组（P ＜0．05）。结论：GnRH －a 联合 LNG －IUS 对腹腔镜保守性手术术后子宫内膜异位症Ⅲ－Ⅳ期患者的疼痛治疗作用确切、长效，值得临床推广。
목적：탐토촉성선격소석방격소격동제（GnRH －a）연합좌결낙잉동궁내완석계통（LNG －IUS）대자궁내막이위증Ⅲ－Ⅳ기환자술후동통적치료효과。방법：회고성분석100례이행보수성복강경수술적자궁내막이위증Ⅲ－Ⅳ기환자，급여 GnRH －a 연합 LNG －IUS 치료적환자50례（실험조）；급여단순 GnRH －a 치료적환자50례（대조조）。술후6개월、12개월수방환자동통평분（VAS 법，B＆B 법）。결과：량조내술후6개월、12개월 VAS、B＆B 평분현저저우술전（P ＜0．05）。대조조술후12개월 VAS、B＆B 평분현저고우술후6개월（P ＜0．05）。실험조술후12개월 VAS、B＆B 평분현저저우대조조（P ＜0．05）。결론：GnRH －a 연합 LNG －IUS 대복강경보수성수술술후자궁내막이위증Ⅲ－Ⅳ기환자적동통치료작용학절、장효，치득림상추엄。
Objective:To observe the efficacy of GnRH analogue combined with LNG -IUS on pelvic pain of stageⅢ -Ⅳendometriosis patients after conservative laparoscopic surgery.Methods:A total of 100 Ⅲ -Ⅳ stage endome-triosis cases,after laparoscopic diagnosis and conservative laparoscopic surgery,50 in experimental group and treated with GnRH analogue combined with LNG -IUS,50 in control group and treated with GnRH analogue.Retrospectively analyzed the pain score of 6 and 12 months postoperation by VAS test and B&B test.Results:In two groups,the VAS score and B&Bscore of 6,12 months postoperation were significantly lower than thatof preoperation(P <0.05).The VAS score and B&B score of 12 months postoperation were significantly higher than that of 6 months in control group (P <0.05).The VAS score and B&B score of experimental group was significantly lower than that of control groupin 12 months postoperation(P <0.05).Conclusion:GnRH analogue combined with LNG -IUS are effective and have long effect,and they are a promising treatment of endometrosis.