CAJ | 학술논문

黏液的产生在维持气道湿化，协助气道上皮细胞功能等方面起着关键作用。然而黏液中主要成分黏蛋白的过量增加却可诱发导致支气管和肺实质结构的破坏，引起诸如慢性阻塞性肺疾病、支气管哮喘等疾病的发生。本文将对气道黏蛋白的生物学特性，在气道中的调控机制及其与呼吸系统疾病关系的研究进展作一综述。
점액적산생재유지기도습화，협조기도상피세포공능등방면기착관건작용。연이점액중주요성분점단백적과량증가각가유발도치지기관화폐실질결구적파배，인기제여만성조새성폐질병、지기관효천등질병적발생。본문장대기도점단백적생물학특성，재기도중적조공궤제급기여호흡계통질병관계적연구진전작일종술。
Mucus production takes an important role in maintaining trachea moisture and assist trachea epitheli a cells effect.But the overproduction of mucin,which is main part of mucus,may results in the damage of bronchus and lung,such as COPD,asthma, cystic pulmonary fibrosis.This paper reviwed articles in recent years about trachea mucin's biologica l characteristics,adjust mechanism and its relationship with respiratory diseases.