CAJ | 학술논문

目的：了解我院老年科医院感染患者病原菌分布特点及其对常用抗菌药物的耐药性。方法采用Vitek-2-Compact仪进行菌株鉴定及药敏试验， WHONET5．6软件进行统计分析。结果共检出病原菌766株，以下呼吸道痰标本检出率最高，占59．9%。病原菌检出前几位的依次是铜绿假单胞菌、大肠埃希菌、金黄色葡萄球菌、肺炎克雷伯菌和鲍曼不动杆菌；大肠埃希菌和肺炎克雷伯菌中产超广谱β-酰胺酶( ESBLs)菌株的阳性率分别为70．4%和58．2%；非发酵菌中，铜绿假单胞菌对多种抗菌药物耐药率仍较低；而鲍曼不动杆菌呈多重耐药，亚胺培南耐药菌株分离率高达63．3%。金黄色葡萄球菌中耐甲氧西林金黄色葡萄球菌( MRSA)的检出率为50．3%。结论老年科主要的病原菌对临床常用抗菌药物耐药严重，临床应加强抗菌药物的合理使用和医院感染监控。
목적：료해아원노년과의원감염환자병원균분포특점급기대상용항균약물적내약성。방법채용Vitek-2-Compact의진행균주감정급약민시험， WHONET5．6연건진행통계분석。결과공검출병원균766주，이하호흡도담표본검출솔최고，점59．9%。병원균검출전궤위적의차시동록가단포균、대장애희균、금황색포도구균、폐염극뢰백균화포만불동간균；대장애희균화폐염극뢰백균중산초엄보β-선알매( ESBLs)균주적양성솔분별위70．4%화58．2%；비발효균중，동록가단포균대다충항균약물내약솔잉교저；이포만불동간균정다중내약，아알배남내약균주분리솔고체63．3%。금황색포도구균중내갑양서림금황색포도구균( MRSA)적검출솔위50．3%。결론노년과주요적병원균대림상상용항균약물내약엄중，림상응가강항균약물적합리사용화의원감염감공。
Objective To study the distribution and antibiotic resistance of pathogens isolated from the de-partment of gerontology of our hospital. Methods The clinical isolates were identified with Vitek-2-Compact. The date was analyzed by WHONET5. 4 software. Results A total of 766 clinical strains were isolated, and 45. 8% of pathogens were found in samples from the sputum specimens. The main pathogens were P. aeruginosa, E. coli, S. au-reus, K. pneumoniae and A. baumanii. 70. 4% of Escherichia coli and 58. 2% of K. pneumoniae produced extended spectrum β-lactamases ( ESBLs) . Among non-fermenters, Pseudomonas aeruginosa was sensitive to the most of anti-microbial agents. A. baumanii were multi-drug resistant and its resistance to carbapenem was up to 63. 3%. MRSA accounted for 50. 3% of S. aureus. Conclusion The pathogens isolated from senile patients are resistant to many an-timicrobial agents, and it is mandatory to take effective antibiotic policy and infection control measures.