CAJ | 학술논문

目的：评估慢性阻塞性肺病评估测试( COPD Assessment Test, CAT )量表与肺功能、呼吸困难评分的关系,探讨CAT评分对识别慢阻肺患者的临床价值。方法对157例患者进行肺功能检查,利用CAT量表、改良英国医学研究委员会呼吸困难评级( Modified Medical Research Council Dyspnea, MMRC)量表进行评分。 SPSS 16．0和GraphPad Prism 5．0对结果进行统计分析。结果例患者中,慢阻肺患者80例,非慢阻肺患者77例。两组的CAT评分差异有统计学意义(P<0．001)。慢阻肺患者的CAT评分和MMRC评级均随着慢性阻塞性肺疾病全球倡议( Global initiative for chronic Obstructive Lung Disease, GOLD)分级增加而增加,慢阻肺组CAT评分与肺功能呈负相关(r=-0．47, P<0．001),和MMRC成正相关(rs =0．68, P<0．001)。CAT评分识别慢阻肺的敏感度78．75%,特异度94．81%,ROC曲线下面积0．93。结论 CAT评分与慢阻肺患者肺功能和MMRC评分均有相关性,对慢阻肺有潜在的诊断价值,可用于慢阻肺患者的筛查与评估。
목적：평고만성조새성폐병평고측시( COPD Assessment Test, CAT )량표여폐공능、호흡곤난평분적관계,탐토CAT평분대식별만조폐환자적림상개치。방법대157례환자진행폐공능검사,이용CAT량표、개량영국의학연구위원회호흡곤난평급( Modified Medical Research Council Dyspnea, MMRC)량표진행평분。 SPSS 16．0화GraphPad Prism 5．0대결과진행통계분석。결과례환자중,만조폐환자80례,비만조폐환자77례。량조적CAT평분차이유통계학의의(P<0．001)。만조폐환자적CAT평분화MMRC평급균수착만성조새성폐질병전구창의( Global initiative for chronic Obstructive Lung Disease, GOLD)분급증가이증가,만조폐조CAT평분여폐공능정부상관(r=-0．47, P<0．001),화MMRC성정상관(rs =0．68, P<0．001)。CAT평분식별만조폐적민감도78．75%,특이도94．81%,ROC곡선하면적0．93。결론 CAT평분여만조폐환자폐공능화MMRC평분균유상관성,대만조폐유잠재적진단개치,가용우만조폐환자적사사여평고。
Objective To explore the relationship of CAT with lung function and dyspnea scale and to evalu-ate the application of CAT scale in chronic obstructive pulmonary disease. Methods The lung function of 157 pa-tients were tested by CAT scores and MMRC scores. Statistic analysis was conducted using SPSS 16. 0 and GraphPad Prism 5. 0. Results 157 patients included 80 cases of COPD and 77 non-COPD cases. CAT scores differed signifi-cantly between patients with or without COPD (P<0. 001). The scores of CAT and MMRC increased in COPD pa-tients with the increasing classification of Global initiative for chronic Obstructive Lung Disease ( GOLD) . The scores of CAT in COPD patients were negatively correlated with pulmonary function (r= -0. 47, P<0. 001), and posi-tively correlated with MMRC scores (rs =0. 68, P<0. 001). The sensitivity and specificity of CAT scores in the di-agnosis of COPD were 78. 75% and 94. 81%. Area under the curve was 0. 93. Conclusion CAT scores are correla-ted with MMRC scores and pulmonary function in COPD patients. CAT has potential values in screening COPD and can be applied in identification and assessment of COPD patients.