CAJ | 학술논문

目的：观察噻托溴铵联合信必可都保治疗稳定期慢性阻塞性肺疾病（ COPD）的效果。方法将100例稳定期COPD患者按入院顺序半随机分为观察组和对照组，每组50例。对照组给予茶碱缓释片常规口服，必要时给予沙丁胺醇气雾剂雾化治疗；观察组给予噻托溴铵联合信必可都保雾化治疗，连续治疗2个月。观察两组患者治疗前后肺功能及血气变化情况。结果观察组患者肺功能改善情况及血氧饱和情况明显优于对照组，且均具有统计学意义（ P＜0．05）。结论噻托溴铵联合信必可都保可明显改善稳定期COPD患者的肺功能状态，有利于改善患者预后，提高生活质量。
목적：관찰새탁추안연합신필가도보치료은정기만성조새성폐질병（ COPD）적효과。방법장100례은정기COPD환자안입원순서반수궤분위관찰조화대조조，매조50례。대조조급여다감완석편상규구복，필요시급여사정알순기무제무화치료；관찰조급여새탁추안연합신필가도보무화치료，련속치료2개월。관찰량조환자치료전후폐공능급혈기변화정황。결과관찰조환자폐공능개선정황급혈양포화정황명현우우대조조，차균구유통계학의의（ P＜0．05）。결론새탁추안연합신필가도보가명현개선은정기COPD환자적폐공능상태，유리우개선환자예후，제고생활질량。
Objective To explore the curative effect of Tiotropium bromide combined with Symbicort turbu-haler on patients with stable COPD.Methods One hundred patients with stable COPD were randomly divided into the observation group and the control group.The control group was given theophylline orally, and if necessary salbu-tamol aerosol atomization treatment was given.The observation group was given Tiotropium bromide and Symbicort turbuhale therapy.For two consecutive months after the treatment, the changes of lung function and blood gas were analyzed and compared between the two groups.Results Lung function and blood oxygen saturation improved better in the observation group than those in the control group(P<0.05).Conclusion Tiotropium bromide combined with symbicort turbuhale can obviously improve the stability state of pulmonary function in COPD patients and improve the prognosis of patients and the quality of life.