CAJ | 학술논문

目的：评估枸橼酸氢钾钠对肾结石患者经皮肾镜取石术后残留结石的清除和预防结石复发的效果。方法选择154例因上尿路结石而行经皮肾镜取石术术后无结石残留或有结石残留的患者被纳入研究。根据结石清除情况将患者分为无残石组84例和有残石组70例，每组再随机分为治疗组和对照组。治疗组给予枸橼酸氢钾钠颗粒治疗，10 g／d，3次／d，疗程3个月；对照组不加用任何药物，饮食要求与治疗组相同，术后12个月比较治疗组和对照组结石复发率或结石生长情况。结果无残石组接受药物治疗的患者12个月后结石复发率显著低于对照组（8．33％ vs 38．46％，P＜0．05），有残石组中接受药物治疗的患者结石增大的比率显著低于对照组（10．71％vs 59．37％，P＜0．05）。结论枸橼酸氢钾钠不仅显著降低经皮肾镜术后结石的复发率，而且抑制术后残留结石的生长。
목적：평고구연산경갑납대신결석환자경피신경취석술후잔류결석적청제화예방결석복발적효과。방법선택154례인상뇨로결석이행경피신경취석술술후무결석잔류혹유결석잔류적환자피납입연구。근거결석청제정황장환자분위무잔석조84례화유잔석조70례，매조재수궤분위치료조화대조조。치료조급여구연산경갑납과립치료，10 g／d，3차／d，료정3개월；대조조불가용임하약물，음식요구여치료조상동，술후12개월비교치료조화대조조결석복발솔혹결석생장정황。결과무잔석조접수약물치료적환자12개월후결석복발솔현저저우대조조（8．33％ vs 38．46％，P＜0．05），유잔석조중접수약물치료적환자결석증대적비솔현저저우대조조（10．71％vs 59．37％，P＜0．05）。결론구연산경갑납불부현저강저경피신경술후결석적복발솔，이차억제술후잔류결석적생장。
Objective To evaluate the efficacy of potassium sodium hydrogen citrate on residual stone re-moval and prevention of stone recurrence after percutaneous nephrolithotomy(PCNL) for renal calculi.Methods One hundred and fifty-four patients with residual stones or without residual stones after PCNL were enrolled in this study.Patients without residual stones(n=84) or with residual stones(n=70) were randomly divided into the treat-ment group and the control group respectively.The treatment group was given orally potassium sodium hydrogen cit-rate granules 10 g per day, and the control group was not treated with any medication.The stone recurrence was com-pared between the two groups after a follow-up of 12 months.Results For patients without residual stones, the stone recurrence rate in the treatment group was significantly lower than that in the control group(8.33%vs 38.46%, P<0.05).For patients with residual stones group, the stone growth rate in the treatment group was also significantly lower than that in the control group(10.71%vs 59.37%, P<0.05).Conclusion Potassium sodium hydrogen cit-rate therapy can not only reduce the stone recurrence, but also inhibit the residual stone growth after PCNL.