CAJ | 학술논문

目的：比较单用泼尼松与泼尼松联合阿昔洛韦治疗急性期 Bell 麻痹的疗效。方法164例发病时间在72h以内的 Bell 麻痹患者。其中,单纯泼尼松治疗组79例,泼尼松联合阿昔洛韦治疗组85例。以 House -Brackmann 分级法作为治疗后3个月面神经功能的评估标准。结果治疗3个月后,泼尼松联合阿昔洛韦治疗组面瘫完全恢复率为87．1%,略高于单用泼尼松组的84．8%(=0．024,P >0．05)。入院时严重瘫痪的患者,联合治疗组面瘫完全恢复率为85．5%,单用泼尼松治疗完全恢复率为81．8%,两组间比较差异无统计学意义(=0．313,P >0．05)。结论早期泼尼松联合阿昔洛韦治疗 Bell 麻痹疗效并不优于单用泼尼松治疗组。
목적：비교단용발니송여발니송연합아석락위치료급성기 Bell 마비적료효。방법164례발병시간재72h이내적 Bell 마비환자。기중,단순발니송치료조79례,발니송연합아석락위치료조85례。이 House -Brackmann 분급법작위치료후3개월면신경공능적평고표준。결과치료3개월후,발니송연합아석락위치료조면탄완전회복솔위87．1%,략고우단용발니송조적84．8%(=0．024,P >0．05)。입원시엄중탄탄적환자,연합치료조면탄완전회복솔위85．5%,단용발니송치료완전회복솔위81．8%,량조간비교차이무통계학의의(=0．313,P >0．05)。결론조기발니송연합아석락위치료 Bell 마비료효병불우우단용발니송치료조。
Objective To compare the therapeutic efficacy of prednisolone alone to acyclovir plus prednisolone in patients with acute idiopathic facial palsy. Methods Using a prospective design. A total of 164 patients suffering from Bell’s plasy within 72 hours after the onset of symptoms were divided into prednisolone group(n = 79)and prednisolone plus acyclovir group(n = 85).The demographic data and clinical characteristics in both groups were collected. Facial nerve function outcomes were evaluated 3 months after the onset with House-Brackmann grading system. Results The proportions of patients who had completely recovered at 3 months in prednisolone plus acyclovir group were slightly higher than that in the prednisolone group(87. 1% vs 84. 8% , =0. 024, P > 0. 05). Patients with severe plasy, the recovery rate that treated with prednisolone plus acyclovir and prednisolone a-lone were 85. 5% and 81. 8% , respectively. There was no significant difference( = 0. 313, P > 0. 05). Conculsion Patients with Bell’s palsy, early treatment with prednisolone in combination with acyclovir is no better than the single treatment with pred-nisolone.