CAJ | 학술논문

目的：探讨合并组织学前列腺炎(HP)对前列腺增生患者的尿动力学参数及尿潴留的影响。方法回顾性分析98例接受经尿道前列腺等离子双极电切术治疗的良性前列腺增生(BPH)患者资料,根据病理诊断分为单纯 BPH 组和 BPH 合并 HP 组,比较国际前列腺症状评分(IPSS)、前列腺体积(PV)、前列腺特异性抗原(PSA)、最大尿流率、最大膀胱容量(MBC)、最大逼尿肌收缩力和膀胱出口梗阻指数(BOOI)等尿动力学指标及膀胱逼尿肌过度活动、尿潴留发生率间的差异。结果与单纯 BPH 组比较,BPH 合并 HP 组具有更高的 IPSS 评分(P =0.020)和 PSA 值(P =0.009),更高的 BOOI 指数(P =0.003),较小的最大膀胱容量(P =0.004),更高的膀胱逼尿肌过度活动的发生率(P =0.041)和尿潴留发生率(P =0.010)。结论合并 HP 的 BPH 患者下尿路症状更重,血清 PSA 升高,导致 MBC 降低、膀胱出口梗阻加重和逼尿肌过度活动的发生等尿动力学参数改变,更易发生尿潴留。
목적：탐토합병조직학전렬선염(HP)대전렬선증생환자적뇨동역학삼수급뇨저류적영향。방법회고성분석98례접수경뇨도전렬선등리자쌍겁전절술치료적량성전렬선증생(BPH)환자자료,근거병리진단분위단순 BPH 조화 BPH 합병 HP 조,비교국제전렬선증상평분(IPSS)、전렬선체적(PV)、전렬선특이성항원(PSA)、최대뇨류솔、최대방광용량(MBC)、최대핍뇨기수축력화방광출구경조지수(BOOI)등뇨동역학지표급방광핍뇨기과도활동、뇨저류발생솔간적차이。결과여단순 BPH 조비교,BPH 합병 HP 조구유경고적 IPSS 평분(P =0.020)화 PSA 치(P =0.009),경고적 BOOI 지수(P =0.003),교소적최대방광용량(P =0.004),경고적방광핍뇨기과도활동적발생솔(P =0.041)화뇨저류발생솔(P =0.010)。결론합병 HP 적 BPH 환자하뇨로증상경중,혈청 PSA 승고,도치 MBC 강저、방광출구경조가중화핍뇨기과도활동적발생등뇨동역학삼수개변,경역발생뇨저류。
Objective To discuss the influence of histological prostatitis (HP)on urodynamic parameters and urinary retention in patients with benign prostatic hyperplasia (BPH ). Methods 98 patients who underwent bipolar transurethral plasmakinetic prostatectomy (TUPKP)due to BPH were retrospectively reviewed and divided into two groups,BPH group and BPH with HP group,based on pathological characteristics of tissue samples. The International prostate symptom score(IPSS),prostate volume(PV),PSA level and urodynamic features including maximum urine flow,maximum bladder capacity, maximum detrusor contractility and bladder outlet obstruction index(BOOI)were compared between the two groups. The occurrence rate of involuntary detrusor contractions and urinary retention were analyzed in both groups. Results Patients in BPH with HP group presented significant higher IPSS total scores (P =0.020),higher PSA level(P =0.009),higher bladder outlet obstruction index (P =0.003)and lower maximum bladder capacity(P =0.004)than the patients in BPH group. Patients in BPH with HP group showed a higher occurrence rate of involuntary detrusor contraction(P =0.041)and urinary retention than that in the other group(P =0.010). Conclusion The occurrence of HP is associated with severer lower urinary tract symptoms,higher PSA level,urodynamic parameters changes such as lower maximum blad-der capacity,severer bladder outlet obstruction,higher proportion of detrusor over activity and urinary re-tention in patients with BPH.