成都医学院学报
成都醫學院學報
성도의학원학보
Journal of Chengdu Medical College
2015年
5期
563-566,603
,共5页
童志远%牟泽东%冉晓辉%颜晓燕
童誌遠%牟澤東%冉曉輝%顏曉燕
동지원%모택동%염효휘%안효연
中药%参七消痞丸%有效成分%提取工艺
中藥%參七消痞汍%有效成分%提取工藝
중약%삼칠소비환%유효성분%제취공예
Chinese medicine%Shenqi Xiaopi pills%Effective component%Extraction process
目的：筛选参七消痞丸中有效成分提取的最佳工艺条件。方法采用平行实验法以出油率为考察指标确定水蒸气蒸馏法提取挥发油的最佳时间。采用正交实验法以出膏率、柴胡总皂苷提取率及柴胡总皂苷含量为考察指标,选取加水倍量和煎煮时间为考察因素,筛选水提取最佳工艺条件。正交实验结果采用综合评分法进行统计分析。结果平行实验结果显示挥发油的最长提取时间为6 h。正交实验结果显示第1次煎煮加水倍量、第2次煎煮时间、第2次煎煮加水倍量3个因素水平综合平均值的最大值分别为 iii=0.738、ii=0.822、iii=0.807,极差分别为0.049、0.229、0.179。结论6 h 可作为参七消痞丸挥发油提取较优工艺条件的一个参考值。其有效成分水提取工艺的较优因素水平搭配为第1次煎煮加水倍量为5倍、第2次煎煮时间为1.5 h、第2次煎煮加水倍量为10倍。
目的：篩選參七消痞汍中有效成分提取的最佳工藝條件。方法採用平行實驗法以齣油率為攷察指標確定水蒸氣蒸餾法提取揮髮油的最佳時間。採用正交實驗法以齣膏率、柴鬍總皂苷提取率及柴鬍總皂苷含量為攷察指標,選取加水倍量和煎煮時間為攷察因素,篩選水提取最佳工藝條件。正交實驗結果採用綜閤評分法進行統計分析。結果平行實驗結果顯示揮髮油的最長提取時間為6 h。正交實驗結果顯示第1次煎煮加水倍量、第2次煎煮時間、第2次煎煮加水倍量3箇因素水平綜閤平均值的最大值分彆為 iii=0.738、ii=0.822、iii=0.807,極差分彆為0.049、0.229、0.179。結論6 h 可作為參七消痞汍揮髮油提取較優工藝條件的一箇參攷值。其有效成分水提取工藝的較優因素水平搭配為第1次煎煮加水倍量為5倍、第2次煎煮時間為1.5 h、第2次煎煮加水倍量為10倍。
목적：사선삼칠소비환중유효성분제취적최가공예조건。방법채용평행실험법이출유솔위고찰지표학정수증기증류법제취휘발유적최가시간。채용정교실험법이출고솔、시호총조감제취솔급시호총조감함량위고찰지표,선취가수배량화전자시간위고찰인소,사선수제취최가공예조건。정교실험결과채용종합평분법진행통계분석。결과평행실험결과현시휘발유적최장제취시간위6 h。정교실험결과현시제1차전자가수배량、제2차전자시간、제2차전자가수배량3개인소수평종합평균치적최대치분별위 iii=0.738、ii=0.822、iii=0.807,겁차분별위0.049、0.229、0.179。결론6 h 가작위삼칠소비환휘발유제취교우공예조건적일개삼고치。기유효성분수제취공예적교우인소수평탑배위제1차전자가수배량위5배、제2차전자시간위1.5 h、제2차전자가수배량위10배。
Objective To select optimum extraction process of effective component in ShenqiXiaopi Pills. Methods As examining index,oil extraction rate of volatile oil was used to determine the best time of steam distillation by method of parallel experiment.As examining index,ratio of extraction,radix bupleuri total saponins extraction yield and content of radix bupleuri total saponins were selected;as study factors,water addition and decoction time were selected to screen optimum process conditions of water extraction by orthogonal experimental method.A comprehensive scoring method was used to analyze results of orthogonal test.Results According to the results of parallel experiment,the longest time of volatile oil extraction was 6 hours.According to the results of orthogonal test,maximum of integrated average of water addition of decoction for the first time,the second decoction time and water addition of decoction for the second time were iii = 0.738,ii = 0.822 and iii = 0.807 respectively.The ranges were 0.049,0.229,and 0.1 79 respectively.Conclusion A period of 6 hours can be used as reference of optimum extraction condition of volatile oil extraction in Shenqi Xiaopi pills.The optimum match of level of factors of effective component water extraction is 5 times of water addition of decoction for the first time, 1.5 hours for the second decoction time,and 10 times of water addition of decoction for the second time.
